Basic Tumor Immunology

Polymorphonuclear myeloid-derived suppressor cells and phosphatidylinositol-3 kinase gamma are critical to tobacco-mimicking oral carcinogenesis in mice
Khoa A Nguyen, Lisa N DePledge, Li Bian, Yao Ke, Von Samedi, Amber A Berning, Philip Owens, Xiao-Jing Wang, Christian D Young

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e007110; DOI: 10.1136/jitc-2023-007110
ATM inhibition augments type I interferon response and antitumor T-cell immunity when combined with radiation therapy in murine tumor models
Won Jong Jin, Luke M Zangl, Meredith Hyun, Elian Massoud, Kaleb Schroeder, Roxana A Alexandridis, Zachary S Morris

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e007474; DOI: 10.1136/jitc-2023-007474
Dynamical modeling of proliferative-invasive plasticity and IFNγ signaling in melanoma reveals mechanisms of PD-L1 expression heterogeneity
Seemadri Subhadarshini, Sarthak Sahoo, Shibjyoti Debnath, Jason A Somarelli, Mohit Kumar Jolly

Journal for ImmunoTherapy of Cancer Sep 2023, 11 (9) e006766; DOI: 10.1136/jitc-2023-006766
NKG2A gene variant predicts outcome of immunotherapy in AML and modulates the repertoire and function of NK cells
Brwa Ali Hussein, Linnea Kristenson, Silvia Pesce, Anne Wöhr, Yarong Tian, Alexander Hallner, Mats Brune, Kristoffer Hellstrand, Ka-Wei Tang, Elin Bernson, Fredrik B Thorén

Journal for ImmunoTherapy of Cancer Aug 2023, 11 (8) e007202; DOI: 10.1136/jitc-2023-007202
Inhibition of tumor intrinsic BANF1 activates antitumor immune responses via cGAS-STING and enhances the efficacy of PD-1 blockade
Minglei Wang, Yiheng Huang, Minxin Chen, Weiyan Wang, Fei Wu, Tao Zhong, Xiaozheng Chen, Fei Wang, Yang Li, Jinming Yu, Meng Wu, Dawei Chen

Journal for ImmunoTherapy of Cancer Aug 2023, 11 (8) e007035; DOI: 10.1136/jitc-2023-007035
Saponin-based adjuvants enhance antigen cross-presentation in human CD11c⁺ CD1c⁺ CD5⁻ CD163⁺ conventional type 2 dendritic cells
Nataschja I Ho, Lisa G M Huis in 't Veld, Jesper van Eck van der Sluijs, Branco M H Heuts, Maaike W G Looman, Esther D Kers-Rebel, Koen van den Dries, Harry Dolstra, Joost H A Martens, Willemijn Hobo, Gosse J Adema

Journal for ImmunoTherapy of Cancer Aug 2023, 11 (8) e007082; DOI: 10.1136/jitc-2023-007082
Id-neoantigen vaccine induces therapeutic CD8⁺ T cells against multiple myeloma: H chain-loss escapees cause FLC MM
Marita Westhrin, Jana Blazevski, Ana Textor, Pegah Abdollahi, Ramakrishna Prabhu Gopalakrishnan, Linda Thuy Ngo, Peter Olaf Hofgaard, Julia Heinzelbecker, Sonja Bobic, Even Fossum, Heidi Cecilie Larsen Spång, Ranveig Braathen, Bjarne Bogen

Journal for ImmunoTherapy of Cancer Aug 2023, 11 (8) e006944; DOI: 10.1136/jitc-2023-006944
C1q⁺ tumor-associated macrophages contribute to immunosuppression through fatty acid metabolic reprogramming in malignant pleural effusion
Siyu Zhang, Wenbei Peng, Haolei Wang, Xuan Xiang, Linlin Ye, Xiaoshan Wei, Zihao Wang, Qianqian Xue, Long Chen, Yuan Su, Qiong Zhou

Journal for ImmunoTherapy of Cancer Aug 2023, 11 (8) e007441; DOI: 10.1136/jitc-2023-007441
TP53 gain-of-function mutation modulates the immunosuppressive microenvironment in non-HPV-associated oral squamous cell carcinoma
Yewen Shi, Xiaoyong Ren, Shaolong Cao, Xi Chen, Bo Yuan, Fabio Henrique Brasil da Costa, Alanis E Rodriguez Rosario, Arnoldo Corona, Chieko Michikawa, Ratna Veeramachaneni, Abdullah A Osman, Tongxin Xie, Wenyi Wang, Andrew G Sikora, Jeffrey N Myers, Roberto Rangel

Journal for ImmunoTherapy of Cancer Aug 2023, 11 (8) e006666; DOI: 10.1136/jitc-2023-006666
Low molecular weight heparin synergistically enhances the efficacy of adoptive and anti-PD-1-based immunotherapy by increasing lymphocyte infiltration in colorectal cancer
Yibo Quan, Jie He, Qi Zou, Liuxi Zhang, Qihui Sun, Hongli Huang, Wanglin Li, Keping Xie, Fang Wei

Journal for ImmunoTherapy of Cancer Aug 2023, 11 (8) e007080; DOI: 10.1136/jitc-2023-007080

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