Basic Tumor Immunology

Tumor-associated macrophage-specific CD155 contributes to M2-phenotype transition, immunosuppression, and tumor progression in colorectal cancer
Xudong Zhu, Rongpu Liang, Tianyun Lan, Dongbing Ding, Shengxin Huang, Jun Shao, Zongheng Zheng, Tufeng Chen, Yong Huang, Jianpei Liu, Janak L Pathak, Hongbo Wei, Bo Wei

Journal for ImmunoTherapy of Cancer Sep 2022, 10 (9) e004219; DOI: 10.1136/jitc-2021-004219
Novel peptide-based vaccine targeting heat shock protein 90 induces effective antitumor immunity in a HER2+ breast cancer murine model
Jinho Kang, Hye-Jin Lee, Jimin Lee, Jinhwa Hong, Yeul Hong Kim, Mary L Disis, Jeong-An Gim, Kyong Hwa Park

Journal for ImmunoTherapy of Cancer Sep 2022, 10 (9) e004702; DOI: 10.1136/jitc-2022-004702
HSP90α induces immunosuppressive myeloid cells in melanoma via TLR4 signaling
Ihor Arkhypov, Feyza Gül Özbay Kurt, Rebekka Bitsch, Daniel Novak, Vera Petrova, Samantha Lasser, Thomas Hielscher, Christopher Groth, Alisa Lepper, Xiaoying Hu, Wei Li, Jochen Utikal, Peter Altevogt, Viktor Umansky

Journal for ImmunoTherapy of Cancer Sep 2022, 10 (9) e005551; DOI: 10.1136/jitc-2022-005551
T cell-intrinsic STING signaling promotes regulatory T cell induction and immunosuppression by upregulating FOXP3 transcription in cervical cancer
Huanhe Ni, Huanling Zhang, Lin Li, He Huang, Hui Guo, Lin Zhang, Chunwei Li, Jing-Xiao Xu, Cai-Ping Nie, Kui Li, Xiaoshi Zhang, Xiaojun Xia, Jiang Li

Journal for ImmunoTherapy of Cancer Sep 2022, 10 (9) e005151; DOI: 10.1136/jitc-2022-005151
Complement downregulation promotes an inflammatory signature that renders colorectal cancer susceptible to immunotherapy
Carsten Krieg, Lukas M Weber, Bruno Fosso, Marinella Marzano, Gary Hardiman, Monica M Olcina, Enric Domingo, Sahar El Aidy, Khalil Mallah, Mark D Robinson, Silvia Guglietta

Journal for ImmunoTherapy of Cancer Sep 2022, 10 (9) e004717; DOI: 10.1136/jitc-2022-004717
Tumorous expression of NAC1 restrains antitumor immunity through the LDHA-mediated immune evasion
Yijie Ren, Anil Kumar, Jugal K Das, Hao-Yun Peng, Liqing Wang, Darby Balllard, Xiaofang Xiong, Xingcong Ren, Yi Zhang, Jin-Ming Yang, Jianxun Song

Journal for ImmunoTherapy of Cancer Sep 2022, 10 (9) e004856; DOI: 10.1136/jitc-2022-004856
Loss of secreted gelsolin enhances response to anticancer therapies
Kok Haw Jonathan Lim, Evangelos Giampazolias, Oliver Schulz, Neil C Rogers, Anna Wilkins, Erik Sahai, Jessica Strid, Caetano Reis e Sousa

Journal for ImmunoTherapy of Cancer Sep 2022, 10 (9) e005245; DOI: 10.1136/jitc-2022-005245
rhIL-7-hyFc and hIL-2/TCB2c combination promotes an immune-stimulatory tumor microenvironment that improves antitumor efficacy of checkpoint inhibitors
Minji Lee, Sun-Kyoung Im, Seungtae Baek, Mankyu Ji, Miyoung Kim, Eun Ju Lee, Seung Taek Ji, Sara Ferrando-Martinez, Alexandra Wolfarth, Jun-Young Lee, Daeun Kim, Donghoon Choi

Journal for ImmunoTherapy of Cancer Mar 2024, 12 (3) e008001; DOI: 10.1136/jitc-2023-008001
Mucosal tumor vaccination delivering endogenous tumor antigens protects against pulmonary breast cancer metastases
Friederike Oltmanns, Ana Vieira Antão, Pascal Irrgang, Vera Viherlehto, Leticia Jörg, Anna Schmidt, Jannik T Wagner, Michael Rückert, Ann-Sophie Flohr, Carol Imanuel Geppert, Benjamin Frey, Wibke Bayer, Claudia Gravekamp, Matthias Tenbusch, Udo Gaipl, Dennis Lapuente

Journal for ImmunoTherapy of Cancer Mar 2024, 12 (3) e008652; DOI: 10.1136/jitc-2023-008652
Hybrid epithelial-mesenchymal status of lung cancer dictates metastatic success through differential interaction with NK cells
Monica Parodi, Giovanni Centonze, Fabio Murianni, Paola Orecchia, Francesca Andriani, Ilaria Roato, Cecilia Gardelli, Melissa Balsamo, Massimo Moro, Giulia Taiè, Ugo Pastorino, Andrea Petretto, Chiara Lavarello ‎, Massimo Milione, Gabriella Sozzi, Luca Roz, Massimo Vitale, Giulia Bertolini

Journal for ImmunoTherapy of Cancer Mar 2024, 12 (3) e007895; DOI: 10.1136/jitc-2023-007895

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