Journal for ImmunoTherapy of Cancer

Phase I/II study of BMS-986156 with ipilimumab or nivolumab with or without stereotactic ablative radiotherapy in patients with advanced solid malignancies
Joe Y Chang, Xinyan Xu, Girish S Shroff, Nathan I Comeaux, Wei Li, Jordi Rodon Ahnert, Daniel D Karp, Ecaterina E Dumbrava, Vivek Verma, Aileen Chen, James Welsh, David S Hong

Journal for ImmunoTherapy of Cancer Oct 2024, 12 (10) e009975; DOI: 10.1136/jitc-2024-009975
HDAC inhibitor SAHA enhances antitumor immunity via the HDAC1/JAK1/FGL1 axis in lung adenocarcinoma
Tingting Xu, Yuan Fang, Yunru Gu, Duo Xu, Tong Hu, Tao Yu, Yang-Yue Xu, Hao-Yang Shen, Pei Ma, Yongqian Shu

Journal for ImmunoTherapy of Cancer Oct 2024, 12 (10) e010077; DOI: 10.1136/jitc-2024-010077
Dendritic cells pulsed with multifunctional Wilms’ tumor 1 (WT1) peptides combined with multiagent chemotherapy modulate the tumor microenvironment and enable conversion surgery in pancreatic cancer
Shigeo Koido, Junichi Taguchi, Masamori Shimabuku, Shin Kan, Tuuse Bito, Takeyuki Misawa, Zensho Ito, Kan Uchiyama, Masayuki Saruta, Shintaro Tsukinaga, Machi Suka, Hiroyuki Yanagisawa, Nobuhiro Sato, Toshifumi Ohkusa, Shigetaka Shimodaira, Haruo Sugiyama

Journal for ImmunoTherapy of Cancer Oct 2024, 12 (10) e009765; DOI: 10.1136/jitc-2024-009765
Novel H-2D^b-restricted CD8 epitope derived from mouse MAGE-type antigen P1A mediates antitumor immunity in C57BL/6 mice
James McAuliffe, Silvia Panetti, Emily Steffke, Amanda Wicki, Vinnycius Pereira-Almeida, Laurine Noblecourt, Yushu Hu, Shi Yu William Guo, Julie Lesenfants, Ramiro Andrei Ramirez-Valdez, Vineethkrishna Chandrasekar, Maryam Ahmad, Vincent Stroobant, Nathalie Vigneron, Benoit J Van den Eynde, Carol Sze Ki Leung

Journal for ImmunoTherapy of Cancer Oct 2024, 12 (10) e008998; DOI: 10.1136/jitc-2024-008998
EASIX-guided risk stratification for complications and outcome after CAR T-cell therapy with ide-cel in relapsed/refractory multiple myeloma
Jan H Frenking, Xiang Zhou, Vivien Wagner, Thomas Hielscher, Joseph Kauer, Elias K Mai, Mirco J Friedrich, Christian S Michel, Marina Hajiyianni, Iris Breitkreutz, Patrick Costello, Omar Nadeem, Niels Weinhold, Hartmut Goldschmidt, Anita Schmitt, Thomas Luft, Michael Schmitt, Carsten Müller-Tidow, Max Topp, Hermann Einsele, Peter Dreger, Nikhil C Munshi, Adam S Sperling, Leo Rasche, Sandra Sauer, Marc S Raab

Journal for ImmunoTherapy of Cancer Oct 2024, 12 (10) e009220; DOI: 10.1136/jitc-2024-009220
NSGS mice humanized with cord blood mononuclear cells show sustained and functional myeloid–lymphoid representation with limited graft-versus-host disease
Carla Panisello, Rosario Aschero, Alba Martinez-Moreno, Heleia Roca Ho, Aida Falgas, Europa Azucena González-Navarro, Julieta Carabelli, Edwards Pradenas, María Lázaro-Díez, Julia G Prado, Julià Blanco, Jorge Carrillo, Manel Juan, Ángel M Carcaboso, Clara Bueno, Pablo Menendez

Journal for ImmunoTherapy of Cancer Oct 2024, 12 (10) e009198; DOI: 10.1136/jitc-2024-009198
PARP inhibitors enhance antitumor immune responses by triggering pyroptosis via TNF–caspase 8–GSDMD/E axis in ovarian cancer
Yu Xia, Pu Huang, Yi-yu Qian, Zanhong Wang, Ning Jin, Xin Li, Wen Pan, Si-Yuan Wang, Ping Jin, Emmanuel Kwateng Drokow, Xiong Li, Qi Zhang, Zhengmao Zhang, Pingfei Li, Yong Fang, Xiang-Ping Yang, Zhiqiang Han, Qing-lei Gao

Journal for ImmunoTherapy of Cancer Oct 2024, 12 (10) e009032; DOI: 10.1136/jitc-2024-009032
Toripalimab in combination with HBM4003, an anti-CTLA-4 heavy chain-only antibody, in advanced melanoma and other solid tumors: an open-label phase I trial
Bixia Tang, Yu Chen, Yu Jiang, Meiyu Fang, Quanli Gao, Xiubao Ren, Li Yao, Gang Huang, Jing Chen, Xiaoshi Zhang, Rongqing Li, Shuai Zhao, Meijuan Gao, Ruixuan Luo, Meng Qi, Feng Li, Fei Zheng, Michael Lee, Xiaolu Tao, Rong Duan, Jun Guo, Zhihong Chi, Chuanliang Cui

Journal for ImmunoTherapy of Cancer Oct 2024, 12 (10) e009662; DOI: 10.1136/jitc-2024-009662
Antigen-independent activation is critical for the durable antitumor effect of GUCY2C-targeted CAR-T cells
Changsong Qi, Dongqun Liu, Chang Liu, Xiaofei Wei, Mingyang Ma, Xinan Lu, Min Tao, Cheng Zhang, Xicheng Wang, Ting He, Jian Li, Fei Dai, Yanping Ding, Lin Shen

Journal for ImmunoTherapy of Cancer Oct 2024, 12 (10) e009960; DOI: 10.1136/jitc-2024-009960
Vaccination generates functional progenitor tumor-specific CD8 T cells and long-term tumor control
Carlos R Detrés Román, Megan M Erwin, Michael W Rudloff, Frank Revetta, Kristen A Murray, Natalie R Favret, Jessica J Roetman, Joseph T Roland, Mary K Washington, Mary Philip

Journal for ImmunoTherapy of Cancer Oct 2024, 12 (10) e009129; DOI: 10.1136/jitc-2024-009129

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