Open access

Immunologically programming the tumor microenvironment induces the pattern recognition receptor NLRC4-dependent antitumor immunity
Xiaofei Yu, Wenjie Liu, Shixian Chen, Xueqian Cheng, Patrick A Paez, Tuanwei Sun, Fang Yuan, Chunyan Wei, Joseph W Landry, Andrew S Poklepovic, Harry D Bear, John R Subjeck, Elizabeth Repasky, Chunqing Guo, Xiang-Yang Wang

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001595; DOI: 10.1136/jitc-2020-001595
Clinical impact of COVID-19 on patients with cancer treated with immune checkpoint inhibition
Aljosja Rogiers, Ines Pires da Silva, Chiara Tentori, Carlo Alberto Tondini, Joseph M Grimes, Megan H Trager, Sharon Nahm, Leyre Zubiri, Michael Manos, Peter Bowling, Arielle Elkrief, Neha Papneja, Maria Grazia Vitale, April A N Rose, Jessica S W Borgers, Severine Roy, Joanna Mangana, Thiago Pimentel Muniz, Tim Cooksley, Jeremy Lupu, Alon Vaisman, Samuel D Saibil, Marcus O Butler, Alexander M Menzies, Matteo S Carlino, Michael Erdmann, Carola Berking, Lisa Zimmer, Dirk Schadendorf, Laura Pala, Paola Queirolo, Christian Posch, Axel Hauschild, Reinhard Dummer, John Haanen, Christian U Blank, Caroline Robert, Ryan J Sullivan, Paolo Antonio Ascierto, Wilson H Miller Jr, F Stephen Hodi, Karijn P M Suijkerbuijk, Kerry L Reynolds, Osama E Rahma, Paul C Lorigan, Richard D Carvajal, Serigne Lo, Mario Mandala, Georgina V Long

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001931; DOI: 10.1136/jitc-2020-001931
Inability of granule polarization by NK cells defines tumor resistance and can be overcome by CAR or ADCC mediated targeting
Jiri Eitler, Natalie Wotschel, Nicole Miller, Laurent Boissel, Hans G Klingemann, Winfried Wels, Torsten Tonn

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001334; DOI: 10.1136/jitc-2020-001334
Rethinking immune checkpoint blockade: ‘Beyond the T cell’
Xiuting Liu, Graham D Hogg, David G DeNardo

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001460; DOI: 10.1136/jitc-2020-001460
Blocking IL-17A enhances tumor response to anti-PD-1 immunotherapy in microsatellite stable colorectal cancer
Chao Liu, Ruiqi Liu, Bojun Wang, Jie Lian, Yang Yao, Haoxiu Sun, Chunhui Zhang, Lin Fang, Xin Guan, Jiaqi Shi, Shuling Han, Fei Zhan, Shengnan Luo, Yuanfei Yao, Tongsen Zheng, Yanqiao Zhang

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001895; DOI: 10.1136/jitc-2020-001895
Correction: Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of lymphoma
Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001235corr1; DOI: 10.1136/jitc-2020-001235corr1
Deletion of Cbl-b inhibits CD8⁺ T-cell exhaustion and promotes CAR T-cell function
Jitendra Kumar, Ritesh Kumar, Amir Kumar Singh, Elviche L Tsakem, Mahesh Kathania, Matthew J Riese, Arianne L Theiss, Marco L Davila, K Venuprasad

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001688; DOI: 10.1136/jitc-2020-001688
Estrogen receptor beta signaling in CD8⁺ T cells boosts T cell receptor activation and antitumor immunity through a phosphotyrosine switch
Bin Yuan, Curtis A Clark, Bogang Wu, Jing Yang, Justin M Drerup, Tianbao Li, Victor X Jin, Yanfen Hu, Tyler J Curiel, Rong Li

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001932; DOI: 10.1136/jitc-2020-001932
CXCL13 shapes immunoactive tumor microenvironment and enhances the efficacy of PD-1 checkpoint blockade in high-grade serous ovarian cancer
Moran Yang, Jiaqi Lu, Guodong Zhang, Yiying Wang, Mengdi He, Qing Xu, Congjian Xu, Haiou Liu

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001136; DOI: 10.1136/jitc-2020-001136
Identification of neuroblastoma cell lines with uncommon TAZ⁺/mesenchymal stromal cell phenotype with strong suppressive activity on natural killer cells
Claudia Canzonetta, Andrea Pelosi, Sabina Di Matteo, Irene Veneziani, Nicola Tumino, Paola Vacca, Enrico Munari, Marco Pezzullo, Charles Theuer, Rita De Vito, Vito Pistoia, Luigi Tomao, Franco Locatelli, Lorenzo Moretta, Ignazio Caruana, Bruno Azzarone

Journal for ImmunoTherapy of Cancer Jan 2021, 9 (1) e001313; DOI: 10.1136/jitc-2020-001313

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