Open access

Prediction of immune checkpoint inhibition with immune oncology-related gene expression in gastrointestinal cancer using a machine learning classifier
Zhihao Lu, Huan Chen, Xi Jiao, Wei Zhou, Wenbo Han, Shuang Li, Chang Liu, Jifang Gong, Jian Li, Xiaotian Zhang, Xicheng Wang, Zhi Peng, Changsong Qi, Zhenghang Wang, Yanyan Li, Jie Li, Yan Li, Malcolm Brock, Henghui Zhang, Lin Shen

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e000631; DOI: 10.1136/jitc-2020-000631
Differential quantities of immune checkpoint-expressing CD8 T cells in soft tissue sarcoma subtypes
Yarne Klaver, Maud Rijnders, Astrid Oostvogels, Rebecca Wijers, Marcel Smid, Dirk Grünhagen, Kees Verhoef, Stefan Sleijfer, Cor Lamers, Reno Debets

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e000271; DOI: 10.1136/jitc-2019-000271
Tumor copy-number alterations predict response to immune-checkpoint-blockade in gastrointestinal cancer
Zhihao Lu, Huan Chen, Shuang Li, Jifang Gong, Jian Li, Jianling Zou, Lihong Wu, Jianing Yu, Wenbo Han, Huaibo Sun, Xi Jiao, Xiaotian Zhang, Zhi Peng, Ming Lu, Zhenghang Wang, Henghui Zhang, Lin Shen

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e000374; DOI: 10.1136/jitc-2019-000374
Enhanced immunotherapeutic profile of oncolytic virus-based cancer vaccination using cyclophosphamide preconditioning
Jonathan G Pol, Matthew J Atherton, Kyle B Stephenson, Byram W Bridle, Samuel T Workenhe, Natasha Kazdhan, AJ Robert McGray, Yonghong Wan, Guido Kroemer, Brian D Lichty

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e000981; DOI: 10.1136/jitc-2020-000981
Safety and efficacy of CAR-T cell targeting BCMA in patients with multiple myeloma coinfected with chronic hepatitis B virus
Lu Han, Jian Zhou, Keshu Zhou, Xinghu Zhu, Lingdi Zhao, Baijun Fang, Qingsong Yin, Xudong Wei, Hu Zhou, Linlin Li, Bengling Xu, Jishuai Zhang, Yongping Song, Quanli Gao

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e000927; DOI: 10.1136/jitc-2020-000927
IL-6 regulates CCR5 expression and immunosuppressive capacity of MDSC in murine melanoma
Rebekka Weber, Zeno Riester, Laura Hüser, Carsten Sticht, Alina Siebenmorgen, Christopher Groth, Xiaoying Hu, Peter Altevogt, Jochen S Utikal, Viktor Umansky

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e000949; DOI: 10.1136/jitc-2020-000949
Subtype and grade-dependent spatial heterogeneity of T-cell infiltration in pediatric glioma
M Hope Robinson, Juan Vasquez, Akhilesh Kaushal, Tobey J MacDonald, José E Velázquez Vega, Matthew Schniederjan, Kavita Dhodapkar

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e001066; DOI: 10.1136/jitc-2020-001066
Clinical activity of pembrolizumab in metastatic prostate cancer with microsatellite instability high (MSI-H) detected by circulating tumor DNA
Pedro Barata, Neeraj Agarwal, Roberto Nussenzveig, Benjamin Gerendash, Ellen Jaeger, Whitley Hatton, Elisa Ledet, Brian Lewis, Jodi Layton, Hani Babiker, Alan Bryce, Rohan Garje, Cy Stein, Lesli Kiedrowski, Philip Saylor, Oliver Sartor

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e001065; DOI: 10.1136/jitc-2020-001065
Efficient elimination of primary B-ALL cells in vitro and in vivo using a novel 4-1BB-based CAR targeting a membrane-distal CD22 epitope
Talia Velasco-Hernandez, Samanta Romina Zanetti, Heleia Roca-Ho, Francisco Gutierrez-Aguera, Paolo Petazzi, Diego Sánchez-Martínez, Oscar Molina, Matteo Libero Baroni, Jose Luis Fuster, Paola Ballerini, Clara Bueno, Narcis Fernandez-Fuentes, Pablo Engel, Pablo Menendez

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e000896; DOI: 10.1136/jitc-2020-000896
Oxazaphosphorines combined with immune checkpoint blockers: dose-dependent tuning between immune and cytotoxic effects
Julia Delahousse, Charles Skarbek, Mélanie Desbois, Jean-Luc Perfettini, Nathalie Chaput, Angelo Paci

Journal for ImmunoTherapy of Cancer Aug 2020, 8 (2) e000916; DOI: 10.1136/jitc-2020-000916

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