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Circulating myeloid-derived suppressor cells and regulatory T cells as immunological biomarkers in refractory/relapsed diffuse large B-cell lymphoma: translational results from the R2-GDP-GOTEL trial
Carlos Jiménez-Cortegana, Natalia Palazón-Carrión, Alejandro Martin Garcia-Sancho, Esteban Nogales-Fernandez, Fernando Carnicero-González, Eduardo Ríos-Herranz, Fatima de la Cruz-Vicente, Guillermo Rodríguez-García, Rubén Fernández-Álvarez, Antonio Rueda Dominguez, Maria Casanova-Espinosa, Natividad Martínez-Banaclocha, Josep Gumà-Padrò, José Gómez-Codina, Jorge Labrador, Antonio Salar-Silvestre, Delvys Rodriguez-Abreu, Laura Galvez-Carvajal, Mariano Provencio, Margarita Sánchez-Beato, María Guirado-Risueño, Pablo Espejo-García, Marylene Lejeune, Tomás Álvaro, Victor Sánchez-Margalet, Luis de la Cruz-Merino

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002323; DOI: 10.1136/jitc-2020-002323
Incidence of immune checkpoint inhibitor–mediated diarrhea and colitis (imDC) in patients with cancer and preexisting inflammatory bowel disease: a propensity score–matched retrospective study
Joseph Sleiman, Wei Wei, Ravi Shah, Muhammad Salman Faisal, Jessica Philpott, Pauline Funchain

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002567; DOI: 10.1136/jitc-2021-002567
Off-tumor IDO1 target engagements determine the cancer-immune set point and predict the immunotherapeutic efficacy
Lin Xie, Kuan Hu, Yanhong Duo, Takashi Shimokawa, Katsushi Kumata, Yiding Zhang, Cuiping Jiang, Lulu Zhang, Nobuki Nengaki, Hidekatsu Wakizaka, Yihai Cao, Ming-Rong Zhang

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002616; DOI: 10.1136/jitc-2021-002616
Novel non-terminal tumor sampling procedure using fine needle aspiration supports immuno-oncology biomarker discovery in preclinical mouse models
Suzanne Isabelle Sitnikova, Sophie Munnings-Tomes, Elena Galvani, Stacy Kentner, Kathy Mulgrew, Chris Rands, Judit España Agustí, Tianhui Zhang, Kristina M Ilieva, Guglielmo Rosignoli, Hormas Ghadially, Matthew J Robinson, Tim Slidel, Robert W Wilkinson, Simon J Dovedi

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002894; DOI: 10.1136/jitc-2021-002894
Cancer environmental immunotherapy: starving tumor cell to death by targeting TGFB on immune cell
Xing Huang, Gang Zhang, Tingbo Liang

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002823; DOI: 10.1136/jitc-2021-002823
S100A4 enhances protumor macrophage polarization by control of PPAR-γ-dependent induction of fatty acid oxidation
Shuangqing Liu, Huilei Zhang, Yanan Li, Yana Zhang, Yangyang Bian, Yanqiong Zeng, Xiaohan Yao, Jiajia Wan, Xu Chen, Jianru Li, Zhaoqing Wang, Zhihai Qin

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002548; DOI: 10.1136/jitc-2021-002548
Pericardial disease in patients treated with immune checkpoint inhibitors
Jingyi Gong, Zsofia Dora Drobni, Amna Zafar, Thiago Quinaglia, Sarah Hartmann, Hannah K Gilman, Vineet K Raghu, Carlos Gongora, Meghan E Sise, Raza M Alvi, Leyre Zubiri, Anju Nohria, Ryan Sullivan, Kerry L Reynolds, Daniel Zlotoff, Tomas G Neilan

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002771; DOI: 10.1136/jitc-2021-002771
STING activation normalizes the intraperitoneal vascular-immune microenvironment and suppresses peritoneal carcinomatosis of colon cancer
Seung Joon Lee, Hannah Yang, Woo Ram Kim, Yu Seong Lee, Won Suk Lee, So Jung Kong, Hye Jin Lee, Jeong Hun Kim, Jaekyung Cheon, Beodeul Kang, Hong Jae Chon, Chan Kim

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002195; DOI: 10.1136/jitc-2020-002195
Massive PD-L1 and CD8 double positive TILs characterize an immunosuppressive microenvironment with high mutational burden in lung cancer
Libin Zhang, Yanhui Chen, Han Wang, Zheyuan Xu, Yang Wang, Sixing Li, Jun Liu, Yun Chen, Hongli Luo, Lijia Wu, Ying Yang, Henghui Zhang, Hao Peng

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002356; DOI: 10.1136/jitc-2021-002356
IL-6 contributes to metastatic switch via the differentiation of monocytic-dendritic progenitors into prometastatic immune cells
Ksenia Magidey-Klein, Tim J Cooper, Ksenya Kveler, Rachelly Normand, Tongwu Zhang, Michael Timaner, Ziv Raviv, Brian P. James, Roi Gazit, Ze'ev A. Ronai, Shai Shen-Orr, Yuval Shaked

Journal for ImmunoTherapy of Cancer Jun 2021, 9 (6) e002856; DOI: 10.1136/jitc-2021-002856

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