Open access

Prophylactic IL-23 blockade uncouples efficacy and toxicity in dual CTLA-4 and PD-1 immunotherapy
Mingyi Ju, Jiaojiao Zhang, Zhuoyuan Deng, Minjie Wei, Lianghua Ma, Ting Chen, Lin Zhao

Journal for ImmunoTherapy of Cancer Jul 2024, 12 (7) e009345; DOI: 10.1136/jitc-2024-009345
Exploring markers of immunoresponsiveness in papillary thyroid carcinoma and future treatment strategies
Atish Mohanty, Michelle Afkhami, Amanda Reyes, Rebecca Pharaon, Holly Yin, Haiqing Li, Dana Do, Diana Bell, Arin Nam, Sue Chang, Thomas Gernon, Robert Kang, Arya Amini, Sagus Sampath, Prakash Kulkarni, Raju Pillai, Vicky Villaflor, Ravi Salgia, Ellie Maghami, Erminia Massarelli

Journal for ImmunoTherapy of Cancer Jul 2024, 12 (7) e008505; DOI: 10.1136/jitc-2023-008505
POSTN⁺ cancer-associated fibroblasts determine the efficacy of immunotherapy in hepatocellular carcinoma
Hao Wang, Yuan Liang, Zheng Liu, Rui Zhang, Jiashuo Chao, Mingming Wang, Mu Liu, Lei Qiao, Zhengfeng Xuan, Haitao Zhao, Ling Lu

Journal for ImmunoTherapy of Cancer Jul 2024, 12 (7) e008721; DOI: 10.1136/jitc-2023-008721
Phase II basket trial of Dual Anti-CTLA-4 and Anti-PD-1 blockade in Rare Tumors (DART) SWOG S1609: adrenocortical carcinoma cohort
Sandip P Patel, Megan Othus, Young Kwang Chae, Tridu Huynh, Benjamin Tan, Timothy Kuzel, Christine McLeod, Gabby Lopez, Helen X Chen, Elad Sharon, Howard Streicher, Christopher W Ryan, Charles Blanke, Razelle Kurzrock

Journal for ImmunoTherapy of Cancer Jul 2024, 12 (7) e009074; DOI: 10.1136/jitc-2024-009074
NAD⁺ metabolism enzyme NNMT in cancer-associated fibroblasts drives tumor progression and resistance to immunotherapy by modulating macrophages in urothelial bladder cancer
Meihua Yang, Bo Wang, Weibin Hou, Honghui Zeng, Wang He, Xin-Ke Zhang, Dong Yan, Hao Yu, Long Huang, Lu Pei, Kaiwen Li, Haide Qin, Tianxin Lin, Jian Huang

Journal for ImmunoTherapy of Cancer Jul 2024, 12 (7) e009281; DOI: 10.1136/jitc-2024-009281
Density of tertiary lymphoid structures predicts clinical outcome in breast cancer brain metastasis
Yuan-Yuan Zhao, Zhen Fan, Bao-Rui Tao, Zun-Guo Du, Zhi-Feng Shi

Journal for ImmunoTherapy of Cancer Jul 2024, 12 (7) e009232; DOI: 10.1136/jitc-2024-009232
TG6050, an oncolytic vaccinia virus encoding interleukin-12 and anti-CTLA-4 antibody, favors tumor regression via profound immune remodeling of the tumor microenvironment
Fadi Azar, Jules Deforges, Christelle Demeusoit, Patricia Kleinpeter, Christelle Remy, Nathalie Silvestre, Johann Foloppe, Laetitia Fend, Clémentine Spring-Giusti, Eric Quéméneur, Jean-Baptiste Marchand

Journal for ImmunoTherapy of Cancer Jul 2024, 12 (7) e009302; DOI: 10.1136/jitc-2024-009302
Treatment-free survival and partitioned survival analysis of patients with advanced renal cell carcinoma treated with nivolumab plus ipilimumab versus sunitinib: 5-year update of CheckMate 214
Charlene M Mantia, Opeyemi A Jegede, Elizabeth R Plimack, Thomas Powles, Robert J Motzer, Nizar M Tannir, Chung-Han Lee, Yoshihiko Tomita, Martin H Voss, Toni K Choueiri, Brian I Rini, Hans J Hammers, Bernard Escudier, Laurence Albigès, Lisa Rosenblatt, Michael B Atkins, Meredith M Regan, David F McDermott

Journal for ImmunoTherapy of Cancer Jul 2024, 12 (7) e009495; DOI: 10.1136/jitc-2024-009495
Combination of oncolytic Maraba virus with immune checkpoint blockade overcomes therapy resistance in an immunologically cold model of advanced melanoma with dysfunctional T-cell receptor signalling
Edward Armstrong, Matthew K L Chiu, Shane Foo, Lizzie Appleton, Pablo Nenclares, Anton Patrikeev, Nitya Mohan, Martin Mclaughlin, Galabina Bozhanova, Julia Hoebart, Victoria Roulstone, Emmanuel Patin, Malin Pedersen, Joan Kyula, Masahiro Ono, Fiona Errington-Mais, John Bell, Kevin J Harrington, Alan Melcher, Victoria Jennings

Journal for ImmunoTherapy of Cancer Jul 2024, 12 (7) e009443; DOI: 10.1136/jitc-2024-009443
Preclinical activity of allogeneic SLAMF7-specific CAR T-cells (UCARTCS1) in multiple myeloma
Charlotte L B M Korst, Chloe O’Neill, Wassilis S C Bruins, Meliha Cosovic, Inoka Twickler, Christie P M Verkleij, Diane Le Clerre, Maria Themeli, Isabelle Chion-Sotinel, Sonja Zweegman, Roman Galetto, Tuna Mutis, Niels W C J van de Donk

Journal for ImmunoTherapy of Cancer Jul 2024, 12 (7) e008769; DOI: 10.1136/jitc-2023-008769

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