Open access

1476 A novel therapeutic approach targeting stroma of pancreatic cancer using an innovative anti-microbial approach
Kajal Gupta, Eileena Giurini

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1640; DOI: 10.1136/jitc-2023-SITC2023.1476
1477 Neuronal modulation of myeloid cells in glioblastoma
John C Hancock, Mark Gilbert

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1641; DOI: 10.1136/jitc-2023-SITC2023.1477
1478 Dipeptidyl peptidase 4 (DPP4) inhibition is not solely responsible for the anti-tumor effects of BXCL701, an inhibitor of multiple DPPs, in a murine model of pancreatic ductal adenocarcinoma
Alexander Lekan, Rachael Maynard, Zoe X Malchiodi, Annie Zuo, Sandra A Jablonski, Veena Agarwal, Moses Donkor, Vincent O’Neill, Louis M Weiner

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1642; DOI: 10.1136/jitc-2023-SITC2023.1478
1479 A Novel TumorGraft3D immune co-culture platform for high throughput immune-oncology screening
Taylor Light, Vaishnavi Sambandam, Samaneh Kamali, Nathan Alban, Yamini Nallana, Salma Shaik, Brandon Walling, Christine Baer, Gilad Silberberg, Veena Jagannathan, Mara Gilardi, Stefano Cairo, Marianna Zipeto, Abhay Andar, Karin Abarca Heidemann, Maria Mancini, Michael Ritchie

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1643; DOI: 10.1136/jitc-2023-SITC2023.1479
1480 Spatially resolved T-cell microenvironment in mantle cell lymphoma using combined image analysis and spatial omics
Lavanya Lokhande, Daniel Nilsson, Joana Rodrigues, May Hassan, Lina Olsson, Anna Porwit, Anna S Gerdtsson, Mats Jerkeman, Sara Ek

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1644; DOI: 10.1136/jitc-2023-SITC2023.1480
1481 Clinicopathological and molecular features of rhabdomyosarcoma influence their immune landscape
Alexandre Maalouf, Aditya Suru, Lindy Zhang, Ada Tam, Thet HK Aye, Christian Meyer, Carol Morris, Adam Levin, Sophia A Strike, Daniel Rhee, Albert Aboulafia, John Gross, Robert Anders, Drew Pardoll, Nicolas Llosa

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1645; DOI: 10.1136/jitc-2023-SITC2023.1481
1482 Spatial characterization of pro-inflammatory pathways in the pathogenesis of IBD-associated colorectal cancer
Kirsteen Maclean, Anna Juncker-Jensen, Qinqin Zha, Lakshmi Chandramohan

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1646; DOI: 10.1136/jitc-2023-SITC2023.1482
1483 Spatial tumor-immune protein signatures and targets associated with prognosis and subtypes of ovarian carcinoma
Constantina Mateoiu, Asger M Frank, Elias Carlsson, Huaqiang Ouyang, Lavanya Lokhande, Sara Ek, Karin Sundfeldt, Anna S Gerdtsson

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1647; DOI: 10.1136/jitc-2023-SITC2023.1483
1484 An interplay between innate/adaptive/humoral immunity leads to increased immunogenicity of melanoma vs. non-melanoma derived brain metastases
Alberto Mendoza Valderrey, Daria M Kessler, Douglas A Hanes, Ludmila Danilova, Ethan Dettmann, Kai Rau, Yueqin Quan, Stacey Stern, Russell C Rockne, Daniel F Kelly, Garni Barkhoudarian, Kim Margolin, Steven E Kolker, Maria L Ascierto

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1648; DOI: 10.1136/jitc-2023-SITC2023.1484
1485 Characterization of the hormone receptor-positive breast tumor microenvironment using single cell transcriptomics and multi-plex immunofluorescence
Daniel E Michaud, Kenichi Shimada, Kelly F Zheng, Cheryl Gu, Yvonne X Cui, Jonathan Goldberg, Esther R Ogayo, Sandro Santagata, Peter K Sorger, Elizabeth A Mittendorf, Jennifer L Guerriero

Journal for ImmunoTherapy of Cancer Nov 2023, 11 (Suppl 1) A1649; DOI: 10.1136/jitc-2023-SITC2023.1485

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