Special collections

An IL-7 fusion protein targeting EDA fibronectin upregulates TCF1 on CD8+ T-cells, preferentially accumulates to neoplastic lesions, and boosts PD-1 blockade
Cesare Di Nitto, Domenico Ravazza, Ettore Gilardoni, Thomas Look, Miaomiao Sun, Eleonora Prodi, Vlad Moisoiu, Christian Pellegrino, Markus G. Manz, Emanuele Puca, Michael Weller, Tobias Weiss, Dario Neri, Roberto De Luca

Journal for ImmunoTherapy of Cancer Aug 2024, 12 (8) e008504; DOI: 10.1136/jitc-2023-008504
Epithelium/imcDC2 axis facilitates the resistance of neoadjuvant anti-PD-1 in human NSCLC
Yongyuan Chen, Zheyu Shao, Zhixing Hao, Zhongwei Xin, Xiaoke Chen, Lijian Huang, Di Chen, Mingjie Lin, Qinyuan Liu, Xia Xu, Jinfan Li, Dang Wu, Jun Yan, Ying Chai, Pin Wu

Journal for ImmunoTherapy of Cancer Aug 2024, 12 (8) e007854; DOI: 10.1136/jitc-2023-007854
Gene panel predicts neoadjuvant chemoimmunotherapy response and benefit from immunotherapy in HER2-negative breast cancer
Xunxi Lu, Zongchao Gou, Hong Chen, Li Li, Fei Chen, Chunjuan Bao, Hong Bu

Journal for ImmunoTherapy of Cancer Aug 2024, 12 (8) e009587; DOI: 10.1136/jitc-2024-009587
Five-year follow-up of neoadjuvant PD-1 inhibitor (sintilimab) in non-small cell lung cancer
Bolun Zhou, Fan Zhang, Wei Guo, Shuhang Wang, Ning Li, Bin Qiu, Liang Zhao, Jian Li, Kang Shao, Qi Xue, Fang Lv, Shugeng Gao

Journal for ImmunoTherapy of Cancer Aug 2024, 12 (8) e009355; DOI: 10.1136/jitc-2024-009355
EphA3-targeted chimeric antigen receptor T cells are effective in glioma and generate curative memory T cell responses
Leesa Lertsumitkul, Melinda Iliopoulos, Stacie S Wang, Sarah J McArthur, Lisa M Ebert, Alexander J Davenport, Raelene Endersby, Jordan R Hansford, Katharine J Drummond, Ryan Cross, Misty R Jenkins

Journal for ImmunoTherapy of Cancer Aug 2024, 12 (8) e009486; DOI: 10.1136/jitc-2024-009486
EphA3 CAR T cells are effective against glioblastoma in preclinical models
Paulo Martins, Rochelle C J D’Souza, Niclas Skarne, Lea Lekieffre, Shane Horsefield, Madusha Ranjankumar, Xiang Li, Thuy T Le, Fiona Smith, Corey Smith, Jacqueline Burrows, Bryan W Day, Rajiv Khanna

Journal for ImmunoTherapy of Cancer Aug 2024, 12 (8) e009403; DOI: 10.1136/jitc-2024-009403
Randomized, open-label, phase 2 study of nivolumab plus ipilimumab or nivolumab monotherapy in patients with advanced or metastatic solid tumors of high tumor mutational burden
Michael Schenker, Mauricio Burotto, Martin Richardet, Tudor-Eliade Ciuleanu, Anthony Gonçalves, Neeltje Steeghs, Patrick Schoffski, Paolo A Ascierto, Michele Maio, Iwona Lugowska, Lorena Lupinacci, Alexandra Leary, Jean-Pierre Delord, Julieta Grasselli, David S P Tan, Jennifer Friedmann, Jacqueline Vuky, Marina Tschaika, Somasekhar Konduru, Sai Vikram Vemula, Ruta Slepetis, Georgia Kollia, Misena Pacius, Quyen Duong, Ning Huang, Parul Doshi, Jonathan Baden, Massimo Di Nicola

Journal for ImmunoTherapy of Cancer Aug 2024, 12 (8) e008872; DOI: 10.1136/jitc-2024-008872
Targeting tumor-associated macrophage-derived CD74 improves efficacy of neoadjuvant chemotherapy in combination with PD-1 blockade for cervical cancer
Zixiang Wang, Bingyu Wang, Yuan Feng, Jinwen Ye, Zhonghao Mao, Teng Zhang, Meining Xu, Wenjing Zhang, Xinlin Jiao, Qing Zhang, Youzhong Zhang, Baoxia Cui

Journal for ImmunoTherapy of Cancer Aug 2024, 12 (8) e009024; DOI: 10.1136/jitc-2024-009024
Phase I studies of davoceticept (ALPN-202), a PD-L1-dependent CD28 co-stimulator and dual PD-L1/CTLA-4 inhibitor, as monotherapy and in combination with pembrolizumab in advanced solid tumors (NEON-1 and NEON-2)
Diwakar Davar, Ludimila Cavalcante, Nehal Lakhani, Justin Moser, Michael Millward, Meredith McKean, Mark Voskoboynik, Rachel E Sanborn, Jaspreet S Grewal, Ajita Narayan, Amita Patnaik, Justin F Gainor, Mario Sznol, Amanda Enstrom, Lori Blanchfield, Heidi LeBlanc, Heather Thomas, Michael J Chisamore, Stanford L Peng, Allison Naumovski

Journal for ImmunoTherapy of Cancer Aug 2024, 12 (8) e009474; DOI: 10.1136/jitc-2024-009474
Blockade of glucose-6-phosphate dehydrogenase induces immunogenic cell death and accelerates immunotherapy
Motoki Nakamura, Tetsuya Magara, Maki Yoshimitsu, Shinji Kano, Hiroshi Kato, Keisuke Yokota, Katsuhiro Okuda, Akimichi Morita

Journal for ImmunoTherapy of Cancer Jul 2024, 12 (7) e008441; DOI: 10.1136/jitc-2023-008441

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