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  • Targeting the CD47/thrombospondin-1 signaling axis regulates immune cell bioenergetics in the tumor microenvironment to potentiate antitumor immune response

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Basic tumor immunology
Original research
Targeting the CD47/thrombospondin-1 signaling axis regulates immune cell bioenergetics in the tumor microenvironment to potentiate antitumor immune response

Authors

  • Elizabeth R Stirling Department of Cancer Biology, Wake Forest Univerisity School of Medicine, Winston-Salem, North Carolina, USA PubMed articlesGoogle scholar articles
  • Masaki Terabe Neuro-Oncology Branch, National Cancer Institute, Bethesda, Maryland, USA PubMed articlesGoogle scholar articles
  • Adam S Wilson Department of Surgery, Wake Forest Univerisity School of Medicine, Winston-Salem, North Carolina, USA PubMed articlesGoogle scholar articles
  • Mitra Kooshki Department of Hematology & Oncology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USADepartment of Radiation Oncology, Wake Forest University School of Medicine, WInston-Salem, North Carolina, USA PubMed articlesGoogle scholar articles
  • Liliya M Yamaleyeva Department of Surgery, Wake Forest Univerisity School of Medicine, Winston-Salem, North Carolina, USA PubMed articlesGoogle scholar articles
  • Martha A Alexander-Miller Department of Microbiology & Immunology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA PubMed articlesGoogle scholar articles
  • Wei Zhang Department of Cancer Biology, Wake Forest Univerisity School of Medicine, Winston-Salem, North Carolina, USAAtrium Health Wake Forest Baptist Medical Center, Comprehensive Cancer Center, Winston-Salem, North Carolina, USA PubMed articlesGoogle scholar articles
  • Lance D Miller Department of Cancer Biology, Wake Forest Univerisity School of Medicine, Winston-Salem, North Carolina, USAAtrium Health Wake Forest Baptist Medical Center, Comprehensive Cancer Center, Winston-Salem, North Carolina, USA PubMed articlesGoogle scholar articles
  • Pierre L Triozzi Department of Cancer Biology, Wake Forest Univerisity School of Medicine, Winston-Salem, North Carolina, USADepartment of Hematology & Oncology, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USAAtrium Health Wake Forest Baptist Medical Center, Comprehensive Cancer Center, Winston-Salem, North Carolina, USA PubMed articlesGoogle scholar articles
  • David R Soto-Pantoja Department of Cancer Biology, Wake Forest Univerisity School of Medicine, Winston-Salem, North Carolina, USADepartment of Surgery, Wake Forest Univerisity School of Medicine, Winston-Salem, North Carolina, USADepartment of Radiation Oncology, Wake Forest University School of Medicine, WInston-Salem, North Carolina, USAAtrium Health Wake Forest Baptist Medical Center, Comprehensive Cancer Center, Winston-Salem, North Carolina, USA PubMed articlesGoogle scholar articles
  1. Correspondence to Dr David R Soto-Pantoja; dsotopan{at}wakehealth.edu
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Citation

Stirling ER, Terabe M, Wilson AS, et al
Targeting the CD47/thrombospondin-1 signaling axis regulates immune cell bioenergetics in the tumor microenvironment to potentiate antitumor immune response
Journal for ImmunoTherapy of Cancer 2022;10:e004712. doi: 10.1136/jitc-2022-004712

Publication history

  • Accepted June 12, 2022
  • First published November 23, 2022.
Online issue publication 
October 18, 2023

  • Supplementary Data

    This web only file has been produced by the BMJ Publishing Group from an electronic file supplied by the author(s) and has not been edited for content.

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.