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Basic tumor immunology
Original research
Loss of YTHDF1 in gastric tumors restores sensitivity to antitumor immunity by recruiting mature dendritic cells

Authors

  • Xiaowu Bai Institute of Digestive Disease and The Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong, ChinaDepartment of Surgery, The Chinese University of Hong Kong, Hong Kong, China PubMed articlesGoogle scholar articles
  • Chi Chun Wong Institute of Digestive Disease and The Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong, China PubMed articlesGoogle scholar articles
  • Yasi Pan Institute of Digestive Disease and The Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong, China PubMed articlesGoogle scholar articles
  • Huarong Chen Institute of Digestive Disease and The Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong, China PubMed articlesGoogle scholar articles
  • Weixin Liu Institute of Digestive Disease and The Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong, China PubMed articlesGoogle scholar articles
  • Jianning Zhai Institute of Digestive Disease and The Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong, China PubMed articlesGoogle scholar articles
  • Wei Kang Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong, China PubMed articlesGoogle scholar articles
  • Yu Shi Institute of Digestive Disease and The Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong, China PubMed articlesGoogle scholar articles
  • Masami Yamamoto Division of Physiological Pathology, School of Veterinary Nursing and Technology, Nippon Veterinary and Life Science University, Tokyo, Japan PubMed articlesGoogle scholar articles
  • Tetsuya Tsukamoto Department of Diagnostic Pathology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan PubMed articlesGoogle scholar articles
  • Sachiyo Nomura Department of Gastrointestinal Surgery, Graduate School of medicine, The University of Tokyo, Tokyo, Japan PubMed articlesGoogle scholar articles
  • Philip Chiu Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China PubMed articlesGoogle scholar articles
  • Jun Yu Institute of Digestive Disease and The Department of Medicine and Therapeutics, State Key Laboratory of Digestive Disease, Li Ka Shing Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong, China PubMed articlesGoogle scholar articles
  • Enders Kwok-wai Ng Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China PubMed articlesGoogle scholar articles
  1. Correspondence to Enders Kwok-wai Ng; endersng{at}surgery.cuhk.edu.hk; Jun Yu; junyu{at}cuhk.edu.hk
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Citation

Bai X, Wong CC, Pan Y, et al
Loss of YTHDF1 in gastric tumors restores sensitivity to antitumor immunity by recruiting mature dendritic cells
Journal for ImmunoTherapy of Cancer 2022;10:e003663. doi: 10.1136/jitc-2021-003663

Publication history

  • Accepted January 26, 2022
  • First published February 22, 2022.
Online issue publication 
October 18, 2023

  • Supplementary Data

    This web only file has been produced by the BMJ Publishing Group from an electronic file supplied by the author(s) and has not been edited for content.

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See https://creativecommons.org/licenses/by/4.0/.