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Original research
IL1R2 increases regulatory T cell population in the tumor microenvironment by enhancing MHC-II expression on cancer-associated fibroblasts

Authors

  • Lujun Chen Department of Tumor Biological Treatment, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaJiangsu Engineering Research Center for Tumor Immunotherapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaInstitute of Cell Therapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, China PubMed articlesGoogle scholar articles
  • Hao Huang Department of Tumor Biological Treatment, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaJiangsu Engineering Research Center for Tumor Immunotherapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaInstitute of Cell Therapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, China PubMed articlesGoogle scholar articles
  • Xiao Zheng Department of Tumor Biological Treatment, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaJiangsu Engineering Research Center for Tumor Immunotherapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaInstitute of Cell Therapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, China PubMed articlesGoogle scholar articles
  • Yuan Li Department of Tumor Biological Treatment, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaJiangsu Engineering Research Center for Tumor Immunotherapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaInstitute of Cell Therapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, China PubMed articlesGoogle scholar articles
  • Junjun Chen Department of Tumor Biological Treatment, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaJiangsu Engineering Research Center for Tumor Immunotherapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaInstitute of Cell Therapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, China PubMed articlesGoogle scholar articles
  • Bo Tan Department of Tumor Biological Treatment, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaJiangsu Engineering Research Center for Tumor Immunotherapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaInstitute of Cell Therapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, China PubMed articlesGoogle scholar articles
  • Yingting Liu Department of Tumor Biological Treatment, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaJiangsu Engineering Research Center for Tumor Immunotherapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaInstitute of Cell Therapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, China PubMed articlesGoogle scholar articles
  • Runzi Sun Department of Tumor Biological Treatment, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaJiangsu Engineering Research Center for Tumor Immunotherapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaInstitute of Cell Therapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, China PubMed articlesGoogle scholar articles
  • Bin Xu Department of Tumor Biological Treatment, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaJiangsu Engineering Research Center for Tumor Immunotherapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaInstitute of Cell Therapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, China PubMed articlesGoogle scholar articles
  • Min Yang Department of Tumor Biological Treatment, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaJiangsu Engineering Research Center for Tumor Immunotherapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaInstitute of Cell Therapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaDepartment of Nephrology, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, China PubMed articlesGoogle scholar articles
  • Bin Li Center for Immune-Related Diseases at Shanghai Institute of Immunology, Department of Respiratory and Critical Care Medicine of Ruijin Hospital, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China PubMed articlesGoogle scholar articles
  • Changping Wu Department of Tumor Biological Treatment, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaJiangsu Engineering Research Center for Tumor Immunotherapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaInstitute of Cell Therapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, China PubMed articlesGoogle scholar articles
  • Binfeng Lu Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA PubMed articlesGoogle scholar articles
  • Jingting Jiang Department of Tumor Biological Treatment, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaJiangsu Engineering Research Center for Tumor Immunotherapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, ChinaInstitute of Cell Therapy, the Third Affiliated Hospital of Soochow University, Jiangsu Changzhou, China PubMed articlesGoogle scholar articles
  1. Correspondence to Professor Jingting Jiang; jiangjingting{at}suda.edu.cn
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Citation

Chen L, Huang H, Zheng X, et al
IL1R2 increases regulatory T cell population in the tumor microenvironment by enhancing MHC-II expression on cancer-associated fibroblasts

Publication history

  • Accepted August 1, 2022
  • First published September 1, 2022.
Online issue publication 
September 01, 2022

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