Article info

Original research
Complement downregulation promotes an inflammatory signature that renders colorectal cancer susceptible to immunotherapy

Authors

  • Carsten Krieg Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina, USAHollings Cancer Center Charleston, Medical University of South Carolina, Charleston, South Carolina, USA PubMed articlesGoogle scholar articles
  • Lukas M Weber Institute of Molecular Life Sciences, University of Zurich, Zurich, SwitzerlandSIB Swiss Institute of Bioinformatics, University of Zurich, Zurich, Switzerland PubMed articlesGoogle scholar articles
  • Bruno Fosso Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies, Consiglio Nazionale delle Ricerche, Bari, Italy PubMed articlesGoogle scholar articles
  • Marinella Marzano Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies, Consiglio Nazionale delle Ricerche, Bari, Italy PubMed articlesGoogle scholar articles
  • Gary Hardiman School of Biological Sciences and Institute for Global Food Security, Queens University of Belfast, Belfast, UK PubMed articlesGoogle scholar articles
  • Monica M Olcina Institute of Radiation Oncology, Medical Research Council Oxford Institute for Radiation Oncology, Oxford, UK PubMed articlesGoogle scholar articles
  • Enric Domingo Institute of Radiation Oncology, Medical Research Council Oxford Institute for Radiation Oncology, Oxford, UK PubMed articlesGoogle scholar articles
  • Sahar El Aidy Host-microbe Metabolic Interactions, Microbiology, University of Groningen, Groningen, The Netherlands PubMed articlesGoogle scholar articles
  • Khalil Mallah Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina, USA PubMed articlesGoogle scholar articles
  • Mark D Robinson Institute of Molecular Life Sciences, University of Zurich, Zurich, SwitzerlandSIB Swiss Institute of Bioinformatics, University of Zurich, Zurich, Switzerland PubMed articlesGoogle scholar articles
  • Silvia Guglietta Hollings Cancer Center Charleston, Medical University of South Carolina, Charleston, South Carolina, USARegenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, South Carolina, USADepartment of Experimental Oncology, IEO European Institute of Oncology IRCCS, Milan, Italy PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Silvia Guglietta; gugliett{at}musc.edu
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Citation

Krieg C, Weber LM, Fosso B, et al
Complement downregulation promotes an inflammatory signature that renders colorectal cancer susceptible to immunotherapy

Publication history

  • Accepted August 29, 2022
  • First published September 22, 2022.
Online issue publication 
September 22, 2022
  • Supplementary Data

    This web only file has been produced by the BMJ Publishing Group from an electronic file supplied by the author(s) and has not been edited for content.

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