Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy

Lars Guelen; Thierry O Fischmann; Jerelyn Wong; Smita Mauze; Marco Guadagnoli; Nikolina Bąbała; Jozef Wagenaars; Veronica Juan; David Rosen; Winnie Prosise; Maurice Habraken; Imke Lodewijks; Danling Gu; Judith Stammen-Vogelzangs; Ying Yu; Jeanne Baker; David Lutje Hulsik; Lilian Driessen-Engels; Dan Malashock; Joost Kreijtz; Astrid Bertens; Evert de Vries; Astrid Bovens; Arne Bramer; Yiwei Zhang; Richard Wnek; Sean Troth; Elliot Chartash; Konstantin Dobrenkov; Svetlana Sadekova; Andrea van Elsas; Jason K Cheung; Laurence Fayadat-Dilman; Jannie Borst; Amy M Beebe; Hans Van Eenennaam

doi:10.1136/jitc-2022-005049

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Clinical/translational cancer immunotherapy

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Preclinical characterization and clinical translation of pharmacodynamic markers for MK-5890: a human CD27 activating antibody for cancer immunotherapy

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