1153 Preclinical activity of C-C chemokine receptor 2 (CCR2)-targeted immune stimulating antibody conjugate (ISAC), motivating clinical testing of TAK-500

Vicky Appleman; Atsushi Matsuda; Michelle Ganno; Angel Maldonado Lopez; Emily Rosentrater; Camilla Christensen; Samantha Merrigan; Hong Myung Lee; Min Young Lee; Linlin Dong; Jian Huang; Natasha Iartchouk; Dong Mei Zhang; Jianing Wang; He Xu; Tomoki Yoneyama; Konstantin Piatkov; Carole Harbison; Adnan Abu-Yousif

doi:10.1136/jitc-2022-SITC2022.1153

Article info

Regular and Young Investigator Award Abstracts

Immune-Stimulants and Immune Modulators

1153 Preclinical activity of C-C chemokine receptor 2 (CCR2)-targeted immune stimulating antibody conjugate (ISAC), motivating clinical testing of TAK-500

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Authors

Vicky Appleman Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA PubMed articles Google scholar articles
Atsushi Matsuda Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA PubMed articles Google scholar articles
Michelle Ganno Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA PubMed articles Google scholar articles
Angel Maldonado Lopez Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA PubMed articles Google scholar articles
Emily Rosentrater Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA PubMed articles Google scholar articles
Camilla Christensen Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA PubMed articles Google scholar articles
Samantha Merrigan Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA PubMed articles Google scholar articles
Hong Myung Lee Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA PubMed articles Google scholar articles
Min Young Lee Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA PubMed articles Google scholar articles
Linlin Dong Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA PubMed articles Google scholar articles
Jian Huang Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA PubMed articles Google scholar articles
Natasha Iartchouk Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA PubMed articles Google scholar articles
Dong Mei Zhang Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA PubMed articles Google scholar articles
Jianing Wang Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA PubMed articles Google scholar articles
He Xu Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA PubMed articles Google scholar articles
Tomoki Yoneyama Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA PubMed articles Google scholar articles
Konstantin Piatkov Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA PubMed articles Google scholar articles
Carole Harbison Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA PubMed articles Google scholar articles
Adnan Abu-Yousif Takeda Development Center Americas, Inc. (TDCA), Lexington, MA, USA PubMed articles Google scholar articles

Citation

Appleman V, Matsuda A, Ganno M, et al

1153 Preclinical activity of C-C chemokine receptor 2 (CCR2)-targeted immune stimulating antibody conjugate (ISAC), motivating clinical testing of TAK-500

Journal for ImmunoTherapy of Cancer 2022;10:doi: 10.1136/jitc-2022-SITC2022.1153

Publication history

First published November 7, 2022.

Online issue publication

April 26, 2023

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