719 Phase 1 study of the porcupine (PORCN) inhibitor RXC004 in combination with the PD-1 inhibitor nivolumab in patients with advanced solid tumors

Natalie Cook; Sarah Blagden; Juanita Lopez; Debashis Sarker; Alastair Greystoke; Saira Bashir; Aglaia Skolariki; Salma ElBadri; Cienne Morton; Ana OrtegoFranco; Shybi MohamedKhan; Catherine Eagle; Eimear Flanagan; Louise Goodwin; Caroline Phillips; Jane Robertson; Craig Tilston; Helen Timmis; Simon Woodcock; Ruth Plummer

doi:10.1136/jitc-2022-SITC2022.0719

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Regular and Young Investigator Award Abstracts

Clinical Trials In Progress

719 Phase 1 study of the porcupine (PORCN) inhibitor RXC004 in combination with the PD-1 inhibitor nivolumab in patients with advanced solid tumors

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Authors

Natalie Cook University of Manchester, The Christi, Manchester, UK PubMed articles Google scholar articles
Sarah Blagden Oxford University Hospitals, Oxford, UK PubMed articles Google scholar articles
Juanita Lopez Royal Marsden Hospital, London, UK PubMed articles Google scholar articles
Debashis Sarker Guy’s Hospital NHS Trust, London, UK PubMed articles Google scholar articles
Alastair Greystoke The Freeman Hospital, Newcastle-upon-Tyne, UK PubMed articles Google scholar articles
Saira Bashir The Freeman Hospital, Newcastle-upon-Tyne, UK PubMed articles Google scholar articles
Aglaia Skolariki Oxford University Hospitals, Oxford, UK PubMed articles Google scholar articles
Salma ElBadri Oxford University Hospitals, Oxford, UK PubMed articles Google scholar articles
Cienne Morton Guy’s Hospital NHS Trust, London, UK PubMed articles Google scholar articles
Ana OrtegoFranco University of Manchester, The Christie, Manchester, UK PubMed articles Google scholar articles
Shybi MohamedKhan Royal Marsden Hospital, London, UK PubMed articles Google scholar articles
Catherine Eagle RedX Pharma Plc, Alderley Edge, UK PubMed articles Google scholar articles
Eimear Flanagan RedX Pharma Plc, Alderley Edge, UK PubMed articles Google scholar articles
Louise Goodwin RedX Pharma Plc, Alderley Edge, UK PubMed articles Google scholar articles
Caroline Phillips RedX Pharma Plc, Alderley Edge, UK PubMed articles Google scholar articles
Jane Robertson RedX Pharma Plc, Alderley Edge, UK PubMed articles Google scholar articles
Craig Tilston RedX Pharma Plc, Alderley Edge, UK PubMed articles Google scholar articles
Helen Timmis RedX Pharma Plc, Alderley Edge, UK PubMed articles Google scholar articles
Simon Woodcock RedX Pharma, Alderley Edge, UK PubMed articles Google scholar articles
Ruth Plummer The Freeman Hospital, Newcastle-upon-Tyne, UK PubMed articles Google scholar articles

Citation

Cook N, Blagden S, Lopez J, et al

719 Phase 1 study of the porcupine (PORCN) inhibitor RXC004 in combination with the PD-1 inhibitor nivolumab in patients with advanced solid tumors

Journal for ImmunoTherapy of Cancer 2022;10:doi: 10.1136/jitc-2022-SITC2022.0719

Publication history

First published November 7, 2022.

Online issue publication

April 26, 2023

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