BYON4228 is a pan-allelic antagonistic SIRPα antibody that potentiates destruction of antibody-opsonized tumor cells and lacks binding to SIRPγ on T cells

Mary J van Helden; Seline A Zwarthoff; Roel J Arends; Inge M J Reinieren-Beeren; Marc C B C Paradé; Lilian Driessen-Engels; Karin de Laat-Arts; Désirée Damming; Ellen W H Santegoeds-Lenssen; Daphne W J van Kuppeveld; Imke Lodewijks; Hugo Olsman; Hanke L Matlung; Katka Franke; Ellen Mattaar-Hepp; Marloes E M Stokman; Benny de Wit; Dirk H R F Glaudemans; Daniëlle E J W van Wijk; Lonnie Joosten-Stoffels; Jan Schouten; Paul J Boersema; Monique van der Vleuten; Jorien W H Sanderink; Wendela A Kappers; Diels van den Dobbelsteen; Marco Timmers; Ruud Ubink; Gerard J A Rouwendal; Gijs Verheijden; Miranda M C van der Lee; Wim H A Dokter; Timo K van den Berg

doi:10.1136/jitc-2022-006567

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Basic tumor immunology

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BYON4228 is a pan-allelic antagonistic SIRPα antibody that potentiates destruction of antibody-opsonized tumor cells and lacks binding to SIRPγ on T cells

	Abstract	Full	Pdf
Apr 2023	871	875	262
Total	871	875	262

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