Table of contents

Clinical/Translational Cancer Immunotherapy

• CD200 in CNS tumor-induced immunosuppression: the role for CD200 pathway blockade in targeted immunotherapy (16 December, 2014) Free

  Christopher L Moertel, Junzhe Xia, Rebecca LaRue, Nate N Waldron, Brian M Andersen, Robert M Prins, Hideho Okada, Andrew M Donson, Nicholas K Foreman, Matthew A Hunt, Christopher A Pennell, Michael R Olin
• Circulating tumor DNA analysis as a real-time method for monitoring tumor burden in melanoma patients undergoing treatment with immune checkpoint blockade (16 December, 2014)

  Evan J Lipson, Victor E Velculescu, Theresa S Pritchard, Mark Sausen, Drew M Pardoll, Suzanne L Topalian, Luis A Diaz
• Response assessment in metastatic melanoma treated with ipilimumab and bevacizumab: CT tumor size and density as markers for response and outcome (18 November, 2014)

  Mizuki Nishino, Anita Giobbie-Hurder, Nikhil H Ramaiya, F Stephen Hodi
• Tetramer guided, cell sorter assisted production of clinical grade autologous NY-ESO-1 specific CD8⁺ T cells

  (14 October, 2014)

  Seth M Pollack, Robin L Jones, Erik A Farrar, Ivy P Lai, Sylvia M Lee, Jianhong Cao, Venu G Pillarisetty, Benjamin L Hoch, Ashley Gullett, Marie Bleakley, Ernest U Conrad, Janet F Eary, Kendall C Shibuya, Edus H Warren, Jason N Carstens, Shelly Heimfeld, Stanley R Riddell, Cassian Yee
• Elucidating immunologic mechanisms of PROSTVAC cancer immunotherapy (14 October, 2014)

  Stefanie J Mandl, Ryan B Rountree, Tracy B dela Cruz, Susan P Foy, Joseph J Cote, Evan J Gordon, Erica Trent, Alain Delcayre, Alex Franzusoff
• MAGE-specific T cells detected directly ex-vivo correlate with complete remission in metastatic breast cancer patients after sequential immune-endocrine therapy (16 September, 2014) Free

  Maxwell Janosky, Rachel L Sabado, Crystal Cruz, Isabelita Vengco, Farah Hasan, Arthur Winer, Linda Moy, Sylvia Adams
• Myeloid derived suppressor and dendritic cell subsets are related to clinical outcome in prostate cancer patients treated with prostate GVAX and ipilimumab (16 September, 2014) Free

  Saskia JAM Santegoets, Anita GM Stam, Sinéad M Lougheed, Helen Gall, Karin Jooss, Natalie Sacks, Kristen Hege, Israel Lowy, Rik J Scheper, Winald R Gerritsen, Alfons JM van den Eertwegh, Tanja D de Gruijl
• A pilot study of autologous tumor lysate-loaded dendritic cell vaccination combined with sunitinib for metastatic renal cell carcinoma (19 August, 2014) Free

  Hirokazu Matsushita, Yutaka Enomoto, Haruki Kume, Tohru Nakagawa, Hiroshi Fukuhara, Motofumi Suzuki, Tetsuya Fujimura, Yukio Homma, Kazuhiro Kakimi
• Treatment of unresectable stage IV metastatic melanoma with aviscumine after anti-neoplastic treatment failure: a phase II, multi-centre study (19 August, 2014) Free

  Uwe Trefzer, Ralf Gutzmer, Tabea Wilhelm, Florian Schenck, Katharina C Kähler, Volkmar Jacobi, Klaus Witthohn, Hans Lentzen, Peter Mohr
• A melanoma helper peptide vaccine increases Th1 cytokine production by leukocytes in peripheral blood and immunized lymph nodes (15 July, 2014) Free

  Patrick M Dillon, Walter C Olson, Andrea Czarkowski, Gina R Petroni, Mark Smolkin, William W Grosh, Kimberly A Chianese-Bullock, Donna H Deacon, Craig L Slingluff
• A phase 2, single-arm study of an autologous dendritic cell treatment against mucin 1 in patients with advanced epithelial ovarian cancer (18 June, 2014)

  Paul LR Mitchell, Michael A Quinn, Peter T Grant, David G Allen, Thomas W Jobling, Shane C White, Anne Zhao, Vaios Karanikas, Hilary Vaughan, Geoffrey Pietersz, Ian FC McKenzie, Sharron E Gargosky, Bruce E Loveland
• Durable responses and reversible toxicity of high-dose interleukin-2 treatment of melanoma and renal cancer in a Community Hospital Biotherapy Program (14 May, 2014) Free

  Roxanne Payne, Lyn Glenn, Helena Hoen, Beverley Richards, John W Smith, Robert Lufkin, Todd S Crocenzi, Walter J Urba, Brendan D Curti
• Cytokine responsiveness of CD8⁺ T cells is a reproducible biomarker for the clinical efficacy of dendritic cell vaccination in glioblastoma patients

  (13 May, 2014) Free

  Richard G Everson, Richard M Jin, Xiaoyan Wang, Michael Safaee, Rudi Scharnweber, Dominique N Lisiero, Horacio Soto, Linda M Liau, Robert M Prins
• Prolonged repeated vaccine immuno-chemotherapy induces long-term clinical responses and survival for advanced metastatic melanoma (15 April, 2014)

  Brendon J Coventry, Carrie A Lilly, Peter Hersey, Antonio Michele, Richard J Bright
• Vaccination with dendritic cells loaded with allogeneic brain tumor cells for recurrent malignant brain tumors induces a CD4⁺IL17⁺ response

  (18 February, 2014)

  Michael R Olin, Walter Low, David H McKenna, Stephen J Haines, Tambra Dahlheimer, David Nascene, Michael P Gustafson, Allan B Dietz, H Brent Clark, Wei Chen, Bruce Blazar, John R Ohlfest, Christopher Moertel
• Recombinant interleukin-21 plus sorafenib for metastatic renal cell carcinoma: a phase 1/2 study (27 January, 2014)

  Shailender Bhatia, Brendan Curti, Marc S Ernstoff, Michael Gordon, Elisabeth I Heath, Wilson H Miller, Igor Puzanov, David I Quinn, Thomas W Flaig, Peter VanVeldhuizen, Kelly Byrnes-Blake, Jeremy A Freeman, Rachel Bittner, Naomi Hunder, Sonia Souza, John A Thompson