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Research Article
Ex vivo Akt inhibition promotes the generation of potent CD19CAR T cells for adoptive immunotherapy

Authors

  • Ryan Urak T cell Therapeutics Research Laboratory, Department of Hematology & Hematopoietic Cell TransplantationCity of Hope National Medical Center 1500 E. Duarte Rd. 91010 Duarte CA USA PubMed articlesGoogle scholar articles
  • Miriam Walter T cell Therapeutics Research Laboratory, Department of Hematology & Hematopoietic Cell TransplantationCity of Hope National Medical Center 1500 E. Duarte Rd. 91010 Duarte CA USA PubMed articlesGoogle scholar articles
  • Laura Lim T cell Therapeutics Research Laboratory, Department of Hematology & Hematopoietic Cell TransplantationCity of Hope National Medical Center 1500 E. Duarte Rd. 91010 Duarte CA USA PubMed articlesGoogle scholar articles
  • ChingLam W. Wong T cell Therapeutics Research Laboratory, Department of Hematology & Hematopoietic Cell TransplantationCity of Hope National Medical Center 1500 E. Duarte Rd. 91010 Duarte CA USA PubMed articlesGoogle scholar articles
  • Lihua E. Budde T cell Therapeutics Research Laboratory, Department of Hematology & Hematopoietic Cell TransplantationCity of Hope National Medical Center 1500 E. Duarte Rd. 91010 Duarte CA USA PubMed articlesGoogle scholar articles
  • Sandra Thomas T cell Therapeutics Research Laboratory, Department of Hematology & Hematopoietic Cell TransplantationCity of Hope National Medical Center 1500 E. Duarte Rd. 91010 Duarte CA USA PubMed articlesGoogle scholar articles
  • Stephen J. Forman T cell Therapeutics Research Laboratory, Department of Hematology & Hematopoietic Cell TransplantationCity of Hope National Medical Center 1500 E. Duarte Rd. 91010 Duarte CA USA PubMed articlesGoogle scholar articles
  • Xiuli Wang T cell Therapeutics Research Laboratory, Department of Hematology & Hematopoietic Cell TransplantationCity of Hope National Medical Center 1500 E. Duarte Rd. 91010 Duarte CA USA PubMed articlesGoogle scholar articles
  1. ↵a rurak{at}coh.org
  2. ↵b mwalter{at}coh.org
  3. ↵c lalim{at}coh.org
  4. ↵d wiwong{at}coh.org
  5. ↵e ebudde{at}coh.org
  6. ↵f SThomas{at}coh.org
  7. ↵g SForman{at}coh.org
  8. ↵h 626-256-4673 xiuwang{at}coh.org
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Citation

Urak R, Walter M, Lim L, et al
Ex vivo Akt inhibition promotes the generation of potent CD19CAR T cells for adoptive immunotherapy
Journal for ImmunoTherapy of Cancer 2017;5:26. doi: 10.1186/s40425-017-0227-4

Publication history

  • Received June 2, 2016
  • Accepted February 17, 2017
  • First published March 21, 2017.
Online issue publication 
February 09, 2021

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© The Author(s). Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.