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Abstract
Following publication of the original article [1], the authors have reported that Fig. 2 and Additional file 1: Figure S1, S2 partially show red scripts.
Philipp Metzger and Sabrina V. Kirchleitner contributed equally to this work.
Max Schnurr and Peter Duewell contributed equally to this work.
The original article can be found online at 10.1186/s40425-019-0778-7
Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
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Philipp Metzger and Sabrina V. Kirchleitner contributed equally to this work.
Max Schnurr and Peter Duewell contributed equally to this work.
The original article can be found online at 10.1186/s40425-019-0778-7
Correction to: J ImmunoTher Cancer (2019) 7:288
https://doi.org/10.1186/s40425-019-0778-7
Following publication of the original article [1], the authors have reported that Fig. 2 and Additional file 1: Figure S1, S2 partially show red scripts.
Poly(I:C)c reduces tumor mass in PDAC concomitant with enhanced T cell activation and reduced suppressive capacity of MDSC. Mice with orthotopic T110299 tumors were treated with poly(I:C)c twice prior to sacrifice at day 21 after tumor induction. a Tumor weights, tumor cell MHC-I expression and (b) serum cytokine levels. c Frequencies of MDSC populations in spleen and tumor of untreated and poly(I:C)c-treated mice. d Surface expression profiles of PD-L1 on MDSC subsets. e Frequencies of T cell populations in spleen and tumor of untreated and poly(I:C)c-treated mice. f-g CD69 and PD-1 surface expression of splenic and tumor-resident T cells. h Representative data of IFN-γ secretion in MDSC / T cell co-cultures, at a ratio of 1:1, following anti-CD3/anti-CD28 mAb-coated beads stimulation for 72 h. i Splenic T cells and MDSC from spleens and tumors of untreated or poly(I:C)c-treated tumor-bearing mice were isolated and co-cultured with CFSE-labeled T cells in increasing effector (E; MDSC) to target (T; T cell) ratios (E:T) of 0.25:1, 0.5:1 and 1:1 in the presence of anti-CD3/anti-CD28 mAb-coated beads. After 72 h CFSE dilution of CD4+ and CD8+ T cells was assessed. a-f Data ± SEM is shown for n = 5 to 8 mice per group. g-h Representative graph of three independent experiments. Data± SEM for n = 2 mice per group,unpaired two-sided students t test (*p < 0.05; **p < 0.01)
In Fig. 2:
A: Red font “MHC-I (MFI x 103)” should change to black font;
C: Red font “0.07” and “M-MDSC” should change to black font.
In Additional file 1: Figure S1, S2:
S1: Red font “Spleen” and “Tumor” should change to black font;
S2: Red font “C”, “D”, “E”, “F”, “G”, “H” should change to black font.
The correct version of the figures can be found below.
The corrections have been implemented in the original article as well.
We apologize for the inconvenience.
Reference
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Footnotes
Supplementary information Supplementary information accompanies this paper at 10.1186/s40425-019-0830-7.