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α-PD-1 therapy elevates Treg/Th balance and increases tumor cell pSmad3 that are both targeted by α-TGFβ antibody to promote durable rejection and immunity in squamous cell carcinomas

Authors

  1. a Eswari.Dodagatta{at}ucsf.edu
  2. b dominique.meyer{at}idorsia.com
  3. c melissa.q.reeves{at}gmail.com
  4. d rpaniagua.md{at}gmail.com
  5. e minh.dong.to{at}gmail.com
  6. f mikhail.binnewies{at}gmail.com
  7. g miranda.broz.1988{at}gmail.com
  8. h hmori{at}ucdavis.edu
  9. i di.wu{at}ucsf.edu
  10. j adoumiem{at}umich.edu
  11. k Reyno.delrosario{at}ucsf.edu
  12. l ouming{at}gmail.com
  13. m tanjabuchmann{at}gmx.at
  14. n liangbj127{at}hotmail.com
  15. o Julia.Malato{at}gene.com
  16. p f.arce{at}ucl.ac.uk
  17. q Dean.Sheppard{at}ucsf.edu
  18. r Byron.Hann{at}ucsf.edu
  19. s amer.m.mirza{at}gmail.com
  20. t s.quezada{at}ucl.ac.uk
  21. u Michael.Rosenblum{at}ucsf.edu
  22. v Matthew.Krummel{at}ucsf.edu
  23. w allan.balmain{at}ucsf.edu
  24. x Rosemary.akhurst{at}ucsf.edu
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Citation

Dodagatta-Marri E, Meyer DS, Reeves MQ, et al
α-PD-1 therapy elevates Treg/Th balance and increases tumor cell pSmad3 that are both targeted by α-TGFβ antibody to promote durable rejection and immunity in squamous cell carcinomas

Publication history

  • Received October 8, 2018
  • Accepted December 20, 2018
  • First published March 4, 2019.
Online issue publication 
January 08, 2022

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