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Clinical/translational cancer immunotherapy
Original research
First in human dose calculation of a single-chain bispecific antibody targeting glioma using the MABEL approach

Authors

  • Teilo H Schaller Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina, United States Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina, United States Department of Pathology, Duke University Medical Center, Durham, North Carolina, United States PubMed articlesGoogle scholar articles
  • David J Snyder Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina, United States Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina, United States PubMed articlesGoogle scholar articles
  • Ivan Spasojevic PK/PD Core Laboratory, Duke Cancer Institute, Durham, North Carolina, United States Department of Medicine, Duke University School of Medicine, Durham, North Carolina, United States PubMed articlesGoogle scholar articles
  • Patrick C Gedeon Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina, United States Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina, United States PubMed articlesGoogle scholar articles
  • Luis Sanchez-Perez Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina, United States Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina, United States PubMed articlesGoogle scholar articles
  • John H Sampson Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina, United States Department of Neurosurgery, Duke University Medical Center, Durham, North Carolina, United States Department of Pathology, Duke University Medical Center, Durham, North Carolina, United States PubMed articlesGoogle scholar articles
  1. Correspondence to Professor John H Sampson; john.sampson{at}duke.edu
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Citation

Schaller TH, Snyder DJ, Spasojevic I, et al
First in human dose calculation of a single-chain bispecific antibody targeting glioma using the MABEL approach
Journal for ImmunoTherapy of Cancer 2020;8:e000213. doi: 10.1136/jitc-2019-000213

Publication history

  • Accepted March 21, 2020
  • First published April 8, 2020.
Online issue publication 
April 08, 2020

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Copyright information

© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See https://creativecommons.org/licenses/by/4.0/.