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  • IL-6 promotes PD-L1 expression in monocytes and macrophages by decreasing protein tyrosine phosphatase receptor type O expression in human hepatocellular carcinoma

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Basic tumor immunology
Original research
IL-6 promotes PD-L1 expression in monocytes and macrophages by decreasing protein tyrosine phosphatase receptor type O expression in human hepatocellular carcinoma

Authors

  • Wenjie Zhang Department of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China PubMed articlesGoogle scholar articles
  • Yang Liu Department of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China PubMed articlesGoogle scholar articles
  • Zhongyi Yan Department of Immunology, Nanjing Medical University, Nanjing, China PubMed articlesGoogle scholar articles
  • Hui Yang Department of Hematology, The first affiliated Hospital to Nanjing Medical University, Nanjing, China PubMed articlesGoogle scholar articles
  • Wei Sun Medical School of Nanjing University, Nanjing, China PubMed articlesGoogle scholar articles
  • Yongliang Yao Department of Clinical Laboratory, Kunshan First People's Hospital, Affiliated to Jiangsu University, Kunshan, China PubMed articlesGoogle scholar articles
  • Yun Chen Department of Immunology, Nanjing Medical University, Nanjing, China Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing Medical University, Nanjing, China Research Center for Clinical Oncology, Jiangsu Cancer Hospital, The Affiliated Cancer Hospital of 15 Nanjing Medical University, Nanjing, China PubMed articlesGoogle scholar articles
  • Runqiu Jiang Department of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, China Medical School of Nanjing University, Nanjing, China Jiangsu Laboratory of Molecular Medicine, Medical School of Nanjing University, Nanjing, China PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Runqiu Jiang; jiangrq{at}nju.edu.cn; Dr Yun Chen; chenyun{at}njmu.edu.cn
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Citation

Zhang W, Liu Y, Yan Z, et al
IL-6 promotes PD-L1 expression in monocytes and macrophages by decreasing protein tyrosine phosphatase receptor type O expression in human hepatocellular carcinoma
Journal for ImmunoTherapy of Cancer 2020;8:e000285. doi: 10.1136/jitc-2019-000285

Publication history

  • Accepted May 14, 2020
  • First published June 24, 2020.
Online issue publication 
January 11, 2022

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See https://creativecommons.org/licenses/by/4.0/.