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Safety, immunogenicity, and clinical efficacy of durvalumab in combination with folate receptor alpha vaccine TPIV200 in patients with advanced ovarian cancer: a phase II trial

Authors

  • Dmitriy Zamarin Department of Medicine, Gynecologic Medical Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, United States Department of Medicine, Weill-Cornell Medical College, New York, NY, United States Ludwig Collaborative Laboratory, Memorial Sloan Kettering Cancer Center, New York, NY, United States Parker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY, United States PubMed articlesGoogle scholar articles
  • Sven Walderich Ludwig Collaborative Laboratory, Memorial Sloan Kettering Cancer Center, New York, NY, United States PubMed articlesGoogle scholar articles
  • Aliya Holland Ludwig Collaborative Laboratory, Memorial Sloan Kettering Cancer Center, New York, NY, United States PubMed articlesGoogle scholar articles
  • Qin Zhou Department of Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, United States PubMed articlesGoogle scholar articles
  • Alexia E Iasonos Department of Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, United States PubMed articlesGoogle scholar articles
  • Jean M Torrisi Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States PubMed articlesGoogle scholar articles
  • Taha Merghoub Ludwig Collaborative Laboratory, Memorial Sloan Kettering Cancer Center, New York, NY, United States Parker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY, United States Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA PubMed articlesGoogle scholar articles
  • Lewis F Chesebrough Department of Medicine, Gynecologic Medical Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, United States PubMed articlesGoogle scholar articles
  • Autumn S Mcdonnell Department of Medicine, Gynecologic Medical Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, United States PubMed articlesGoogle scholar articles
  • Jacqueline M Gallagher Department of Medicine, Gynecologic Medical Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, United States PubMed articlesGoogle scholar articles
  • Yanyun Li Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, United States PubMed articlesGoogle scholar articles
  • Travis J Hollmann Parker Institute for Cancer Immunotherapy, Memorial Sloan Kettering Cancer Center, New York, NY, United States Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, United States PubMed articlesGoogle scholar articles
  • Rachel N Grisham Department of Medicine, Gynecologic Medical Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, United States Department of Medicine, Weill-Cornell Medical College, New York, NY, United States PubMed articlesGoogle scholar articles
  • Courtney L Erskine Department of Immunology, Mayo Clinic, Rochester, MN, United States PubMed articlesGoogle scholar articles
  • Mathew S Block Department of Oncology, Mayo Clinic, Rochester, MN, United States PubMed articlesGoogle scholar articles
  • Keith L Knutson Department of Immunology, Mayo Clinic, Rochester, MN, United States PubMed articlesGoogle scholar articles
  • Roisin E O’Cearbhaill Department of Medicine, Gynecologic Medical Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, United States Department of Medicine, Weill-Cornell Medical College, New York, NY, United States PubMed articlesGoogle scholar articles
  • Carol Aghajanian Department of Medicine, Gynecologic Medical Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, United States Department of Medicine, Weill-Cornell Medical College, New York, NY, United States PubMed articlesGoogle scholar articles
  • Jason A Konner Department of Medicine, Gynecologic Medical Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, United States Department of Medicine, Weill-Cornell Medical College, New York, NY, United States PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Dmitriy Zamarin; zamarind{at}mskcc.org
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Citation

Zamarin D, Walderich S, Holland A, et al
Safety, immunogenicity, and clinical efficacy of durvalumab in combination with folate receptor alpha vaccine TPIV200 in patients with advanced ovarian cancer: a phase II trial

Publication history

  • Accepted April 14, 2020
  • First published June 4, 2020.
Online issue publication 
June 04, 2020

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