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Prediction of immune checkpoint inhibition with immune oncology-related gene expression in gastrointestinal cancer using a machine learning classifier

Authors

  • Zhihao Lu Department of Gastrointestinal Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China PubMed articlesGoogle scholar articles
  • Huan Chen Genecast Precision Medicine Technology Institute, Beijing, China PubMed articlesGoogle scholar articles
  • Xi Jiao Department of Gastrointestinal Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China PubMed articlesGoogle scholar articles
  • Wei Zhou Genecast Precision Medicine Technology Institute, Beijing, China PubMed articlesGoogle scholar articles
  • Wenbo Han Genecast Precision Medicine Technology Institute, Beijing, China PubMed articlesGoogle scholar articles
  • Shuang Li Department of Gastrointestinal Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China PubMed articlesGoogle scholar articles
  • Chang Liu Department of Gastrointestinal Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China PubMed articlesGoogle scholar articles
  • Jifang Gong Department of Gastrointestinal Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China PubMed articlesGoogle scholar articles
  • Jian Li Department of Gastrointestinal Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China PubMed articlesGoogle scholar articles
  • Xiaotian Zhang Department of Gastrointestinal Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China PubMed articlesGoogle scholar articles
  • Xicheng Wang Department of Gastrointestinal Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China PubMed articlesGoogle scholar articles
  • Zhi Peng Department of Gastrointestinal Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China PubMed articlesGoogle scholar articles
  • Changsong Qi Department of Gastrointestinal Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China PubMed articlesGoogle scholar articles
  • Zhenghang Wang Department of Gastrointestinal Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China PubMed articlesGoogle scholar articles
  • Yanyan Li Department of Gastrointestinal Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China PubMed articlesGoogle scholar articles
  • Jie Li Department of Gastrointestinal Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China PubMed articlesGoogle scholar articles
  • Yan Li Department of Gastrointestinal Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China PubMed articlesGoogle scholar articles
  • Malcolm Brock Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Henghui Zhang Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China PubMed articlesGoogle scholar articles
  • Lin Shen Department of Gastrointestinal Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China PubMed articlesGoogle scholar articles
  1. Correspondence to Professor Lin Shen, Department of Gastrointestinal Oncology, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China; shenlin{at}bjmu.edu.cn; Dr Henghui Zhang, Institute of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University, Beijing, China; zhhbao{at}ccmu.edu.cn
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Citation

Lu Z, Chen H, Jiao X, et al
Prediction of immune checkpoint inhibition with immune oncology-related gene expression in gastrointestinal cancer using a machine learning classifier

Publication history

  • Accepted July 22, 2020
  • First published August 13, 2020.
Online issue publication 
August 13, 2020

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