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  • Somatic POLE exonuclease domain mutations elicit enhanced intratumoral immune responses in stage II colorectal cancer

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Immunotherapy biomarkers
Short report
Somatic POLE exonuclease domain mutations elicit enhanced intratumoral immune responses in stage II colorectal cancer

Authors

  • Shaobo Mo Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, Shanghai, China PubMed articlesGoogle scholar articles
  • Xiaoji Ma Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, Shanghai, China PubMed articlesGoogle scholar articles
  • Yaqi Li Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, Shanghai, China PubMed articlesGoogle scholar articles
  • Long Zhang Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, Shanghai, China Department of Cancer Institute, Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China PubMed articlesGoogle scholar articles
  • Ting Hou Burning Rock Biotech, Guangdong, China PubMed articlesGoogle scholar articles
  • Han Han-Zhang Burning Rock Biotech, Guangdong, China PubMed articlesGoogle scholar articles
  • Juanjuan Qian Genecast Precision Medicine Technology Institute, Beijing, China PubMed articlesGoogle scholar articles
  • Sanjun Cai Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, Shanghai, China Department of Cancer Institute, Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China PubMed articlesGoogle scholar articles
  • Dan Huang Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, Shanghai, China Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China PubMed articlesGoogle scholar articles
  • Junjie Peng Department of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, Shanghai, China Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, Shanghai, China PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Junjie Peng; pengjj67{at}hotmail.com; Dr Dan Huang; dianehuangfdcc{at}163.com; Dr Sanjun Cai; caisanjuncsj{at}163.com
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Citation

Mo S, Ma X, Li Y, et al
Somatic POLE exonuclease domain mutations elicit enhanced intratumoral immune responses in stage II colorectal cancer
Journal for ImmunoTherapy of Cancer 2020;8:e000881. doi: 10.1136/jitc-2020-000881

Publication history

  • Accepted July 15, 2020
  • First published August 27, 2020.
Online issue publication 
August 27, 2020

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See https://creativecommons.org/licenses/by/4.0/.