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Immune cell therapies and immune cell engineering
Original research
Cell-based artificial APC resistant to lentiviral transduction for efficient generation of CAR-T cells from various cell sources

Authors

  • Andrea Schmidts Cellular Immunotherapy Program, Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Leah C Marsh Cellular Immunotherapy Program, Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Ambike A Srivastava Cellular Immunotherapy Program, Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Amanda A Bouffard Cellular Immunotherapy Program, Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Angela C Boroughs Cellular Immunotherapy Program, Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Irene Scarfò Cellular Immunotherapy Program, Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Rebecca C Larson Cellular Immunotherapy Program, Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Felipe Bedoya Cellular Immunotherapy Program, Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Bryan D Choi Cellular Immunotherapy Program and Department of Neurosurgery, Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Matthew J Frigault Cellular Immunotherapy Program, Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Stefanie R Bailey Cellular Immunotherapy Program, Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Mark B Leick Cellular Immunotherapy Program, Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Sonika Vatsa Cellular Immunotherapy Program, Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Michael C Kann Cellular Immunotherapy Program, Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Michelle S Prew Molecular Pathology Unit, Massachusetts General Hospital, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Benjamin P Kleinstiver Center for Genomic Medicine and Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • J Keith Joung Molecular Pathology Unit, Massachusetts General Hospital, Boston, Massachusetts, USA Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Marcela V Maus Cellular Immunotherapy Program, Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Marcela V Maus; mvmaus{at}mgh.harvard.edu
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Citation

Schmidts A, Marsh LC, Srivastava AA, et al
Cell-based artificial APC resistant to lentiviral transduction for efficient generation of CAR-T cells from various cell sources
Journal for ImmunoTherapy of Cancer 2020;8:e000990. doi: 10.1136/jitc-2020-000990

Publication history

  • Accepted July 2, 2020
  • First published September 7, 2020.
Online issue publication 
September 07, 2020

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.