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484 Bioturing browser: interactively explore public single cell sequencing data
  1. Son Pham,
  2. Tri Le,
  3. Tan Phan,
  4. Minh Pham,
  5. Huy Nguyen,
  6. Loc Lam,
  7. Nam Phung,
  8. Tuan Tran,
  9. Duy Phung,
  10. Thang Tran,
  11. Hoa Pham,
  12. Khoa Nguyen,
  13. Ha-An Nguyen,
  14. Trang Nguyen,
  15. Tam Luu and
  16. Hao Tran
  1. BiTuring Inc., San Diego, CA, USA


Background Single-cell sequencing technology has opened an unprecedented ability to interrogate cancer. It reveals significant insights into the intratumoral heterogeneity, metastasis, therapeutic resistance, which facilitates target discovery and validation in cancer treatment. With rapid advancements in throughput and strategies, a particular immuno-oncology study can produce multi-omics profiles for several thousands of individual cells. This overflow of single-cell data poses formidable challenges, including standardizing data formats across studies, performing reanalysis for individual datasets and meta-analysis.

Methods N/A

Results We present BioTuring Browser, an interactive platform for accessing and reanalyzing published single-cell omics data. The platform is currently hosting a curated database of more than 10 million cells from 247 projects, covering more than 120 immune cell types and subtypes, and 15 different cancer types. All data are processed and annotated with standardized labels of cell types, diseases, therapeutic responses, etc. to be instantly accessed and explored in a uniform visualization and analytics interface. Based on this massive curated database, BioTuring Browser supports searching similar expression profiles, querying a target across datasets and automatic cell type annotation. The platform supports single-cell RNA-seq, CITE-seq and TCR-seq data. BioTuring Browser is now available for download at

Conclusions N/A

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See:

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