Article info

Original research
Targeting PARP-1 with metronomic therapy modulates MDSC suppressive function and enhances anti-PD-1 immunotherapy in colon cancer

Authors

  • Mohamed A Ghonim The Stanley Scott Cancer Center/Louisiana Cancer Research Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USADepartment of Microbiology and Immunology, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt PubMed articlesGoogle scholar articles
  • Salome V Ibba The Stanley Scott Cancer Center/Louisiana Cancer Research Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA PubMed articlesGoogle scholar articles
  • Abdelmetalab F Tarhuni The Stanley Scott Cancer Center/Louisiana Cancer Research Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA PubMed articlesGoogle scholar articles
  • Youssef Errami The Stanley Scott Cancer Center/Louisiana Cancer Research Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA PubMed articlesGoogle scholar articles
  • Hanh H Luu The Stanley Scott Cancer Center/Louisiana Cancer Research Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA PubMed articlesGoogle scholar articles
  • Matthew J Dean The Stanley Scott Cancer Center/Louisiana Cancer Research Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA PubMed articlesGoogle scholar articles
  • Ali H El-Bahrawy The Stanley Scott Cancer Center/Louisiana Cancer Research Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USADepartment of Pharmacology, Faculty of Pharmacy, Al- Azhar University, Assiut, Egypt PubMed articlesGoogle scholar articles
  • Dorota Wyczechowska The Stanley Scott Cancer Center/Louisiana Cancer Research Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA PubMed articlesGoogle scholar articles
  • Ilyes A Benslimane The Stanley Scott Cancer Center/Louisiana Cancer Research Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA PubMed articlesGoogle scholar articles
  • Luis Del Valle The Stanley Scott Cancer Center/Louisiana Cancer Research Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA PubMed articlesGoogle scholar articles
  • Amir A Al-Khami The Stanley Scott Cancer Center/Louisiana Cancer Research Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USAFaculty of Science, Tanta University, Tanta, Egypt PubMed articlesGoogle scholar articles
  • Augusto C Ochoa The Stanley Scott Cancer Center/Louisiana Cancer Research Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA PubMed articlesGoogle scholar articles
  • A Hamid Boulares The Stanley Scott Cancer Center/Louisiana Cancer Research Center, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA PubMed articlesGoogle scholar articles
  1. Correspondence to Professor A Hamid Boulares; hboulr{at}lsuhsc.edu
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Citation

Ghonim MA, Ibba SV, Tarhuni AF, et al
Targeting PARP-1 with metronomic therapy modulates MDSC suppressive function and enhances anti-PD-1 immunotherapy in colon cancer

Publication history

  • Accepted December 20, 2020
  • First published January 25, 2021.
Online issue publication 
November 23, 2023
  • Supplementary Data

    This web only file has been produced by the BMJ Publishing Group from an electronic file supplied by the author(s) and has not been edited for content.

  • Supplementary Data

    This web only file has been produced by the BMJ Publishing Group from an electronic file supplied by the author(s) and has not been edited for content.

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