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Original research
Aged neutrophils form mitochondria-dependent vital NETs to promote breast cancer lung metastasis

Authors

  • Chenghui Yang Key Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaDepartment of Breast Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaCancer Center, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaDepartment of Breast Surgery, The First Affiliated Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China PubMed articlesGoogle scholar articles
  • Zhen Wang Key Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaDepartment of Breast Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaCancer Center, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China PubMed articlesGoogle scholar articles
  • Lili Li Key Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaDepartment of Breast Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaDepartment of Oncology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China PubMed articlesGoogle scholar articles
  • Zhigang Zhang Key Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaDepartment of Gynecology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China PubMed articlesGoogle scholar articles
  • Xiaoyan Jin Key Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaDepartment of Surgical Oncology, Zhejiang Taizhou Municipal Hospital, Taizhou, Zhejiang, People's Republic of China PubMed articlesGoogle scholar articles
  • Pin Wu Key Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaDepartment of Thoracic Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China PubMed articlesGoogle scholar articles
  • Shanshan Sun Key Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaDepartment of Breast Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaCancer Center, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China PubMed articlesGoogle scholar articles
  • Jun Pan Key Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaDepartment of Breast Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaCancer Center, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China PubMed articlesGoogle scholar articles
  • Ke Su Key Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaDepartment of Breast Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaCancer Center, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China PubMed articlesGoogle scholar articles
  • Fang Jia Key Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaDepartment of Breast Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaCancer Center, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China PubMed articlesGoogle scholar articles
  • Leyi Zhang Key Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaDepartment of Breast Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaCancer Center, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China PubMed articlesGoogle scholar articles
  • Haijun Wang Department of Pathology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China PubMed articlesGoogle scholar articles
  • Xiuyan Yu Key Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaDepartment of Breast Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China PubMed articlesGoogle scholar articles
  • Xuan Shao Key Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaDepartment of Breast Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China PubMed articlesGoogle scholar articles
  • Ke Wang Key Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaDepartment of Breast Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China PubMed articlesGoogle scholar articles
  • Fuming Qiu Key Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaDepartment of Oncology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China PubMed articlesGoogle scholar articles
  • Jun Yan Department of Medicine and Department of Microbiology and Immunology, James Graham Brown Cancer Center, University of Louisville, Louisville, Kentucky, USA PubMed articlesGoogle scholar articles
  • Jian Huang Key Laboratory of Tumor Microenvironment and Immune Therapy of Zhejiang Province, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaDepartment of Breast Surgery, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of ChinaCancer Center, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Jian Huang; drhuangjian{at}zju.edu.cn
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Citation

Yang C, Wang Z, Li L, et al
Aged neutrophils form mitochondria-dependent vital NETs to promote breast cancer lung metastasis

Publication history

  • Accepted September 23, 2021
  • First published October 29, 2021.
Online issue publication 
October 29, 2021

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