Article info

Original research
Engineering CAR-NK cells to secrete IL-15 sustains their anti-AML functionality but is associated with systemic toxicities

Authors

  • Ilias Christodoulou Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USADepartment of Internal Medicine, University of Patras School of Health Sciences, Patras, Western Greece, Greece PubMed articlesGoogle scholar articles
  • Won Jin Ho Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Andrew Marple Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Jonas W Ravich Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Ada Tam Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Ruyan Rahnama Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USADepartment of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Adam Fearnow Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Cambrynne Rietberg Department of Pediatrics, University of Michigan, Ann Arbor, Michigan, USA PubMed articlesGoogle scholar articles
  • Sean Yanik Department of Pediatrics, University of Michigan, Ann Arbor, Michigan, USA PubMed articlesGoogle scholar articles
  • Elena E Solomou Department of Internal Medicine, University of Patras School of Health Sciences, Patras, Western Greece, Greece PubMed articlesGoogle scholar articles
  • Ravi Varadhan Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Michael A Koldobskiy Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USADepartment of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Challice L Bonifant Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USADepartment of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Challice L Bonifant; cbonifa2{at}jh.edu
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Citation

Christodoulou I, Ho WJ, Marple A, et al
Engineering CAR-NK cells to secrete IL-15 sustains their anti-AML functionality but is associated with systemic toxicities

Publication history

  • Accepted November 14, 2021
  • First published December 12, 2021.
Online issue publication 
October 25, 2022

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