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  • Single-cell RNA sequencing reveals distinct cellular factors for response to immunotherapy targeting CD73 and PD-1 in colorectal cancer

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Immunotherapy biomarkers
Original research
Single-cell RNA sequencing reveals distinct cellular factors for response to immunotherapy targeting CD73 and PD-1 in colorectal cancer

Authors

  • Miok Kim Therapeutics & Biotechnology Division, Drug Discovery Platform Research Center, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea PubMed articlesGoogle scholar articles
  • Yong Ki Min Therapeutics & Biotechnology Division, Drug Discovery Platform Research Center, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea PubMed articlesGoogle scholar articles
  • Jinho Jang Department of Biomedical Engineering, Ulsan National Institute of Science and Technology, Ulsan, Republic of KoreaKorean Genomics Center, UNIST, Ulsan, Republic of Korea PubMed articlesGoogle scholar articles
  • Hyejin Park Therapeutics & Biotechnology Division, Drug Discovery Platform Research Center, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea PubMed articlesGoogle scholar articles
  • Semin Lee Department of Biomedical Engineering, Ulsan National Institute of Science and Technology, Ulsan, Republic of KoreaKorean Genomics Center, UNIST, Ulsan, Republic of Korea PubMed articlesGoogle scholar articles
  • Chang Hoon Lee Therapeutics & Biotechnology Division, Drug Discovery Platform Research Center, Korea Research Institute of Chemical Technology, Daejeon, Republic of Korea PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Chang Hoon Lee; redmour0{at}gmail.com; Professor Semin Lee; seminlee{at}unist.ac.kr
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Citation

Kim M, Min YK, Jang J, et al
Single-cell RNA sequencing reveals distinct cellular factors for response to immunotherapy targeting CD73 and PD-1 in colorectal cancer
Journal for ImmunoTherapy of Cancer 2021;9:e002503. doi: 10.1136/jitc-2021-002503

Publication history

  • Accepted June 14, 2021
  • First published July 12, 2021.
Online issue publication 
July 12, 2021

  • Supplementary Data

    This web only file has been produced by the BMJ Publishing Group from an electronic file supplied by the author(s) and has not been edited for content.

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.