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Adoptive immunotherapy 101, 104, 118, 130, 157, 162, 164, 166, 169, 171, 172, 174, 175, 176, 177, 178, 179, 181, 184, 185, 186, 187, 189, 190, 191, 192, 193, 200, 201, 204, 205, 209, 210, 215, 220, 223, 225, 226, 384, 385, 400, 458, 543, 544, 610, 651, 668, 688, 708, 714, 912, 97

Angiogenesis 762, 773

Antibody 159, 197, 397, 441, 443, 456, 474, 524, 563, 566, 575, 590, 606, 617, 650, 699, 703, 704, 781, 784, 840, 845, 857, 867, 879, 883

Antigen presenting cells 202, 211, 214, 264, 367, 581, 595, 605, 654, 657, 658, 667, 680, 682, 683, 684, 695, 726, 739, 764, 769, 779, 846, 853, 910, 929, 936, 939

Autoimmunity 236, 724

B cell 423, 47, 506, 747, 839

Bioinformatics 334, 38, 554, 564, 644, 65, 653, 68, 689, 833, 911, 920, 927

Biomarkers 29, 292, 3, 31, 32, 331, 353, 369, 375, 390, 41, 46, 48, 50, 521, 526, 54, 70, 72, 740, 818, 822, 829, 830, 837, 866, 870, 90, 92, 930, 937, 938, 94

Bispecifics 444, 538, 546, 720, 793, 826, 868, 880, 881, 882, 887, 888

CAR T cells 106, 108, 127, 137, 140, 449, 552, 871

Carcinogenesis 776, 907

Checkpoint blockade 232, 237, 238, 239, 243, 248, 255, 256, 278, 281, 285, 287, 293, 295, 296, 301, 302, 303, 305, 309, 314, 316, 317, 319, 320, 322, 326, 327, 342, 347, 349, 350, 351, 359, 381, 382, 383, 398, 4, 402, 420, 421, 425, 435, 440, 477, 483, 484, 485, 488, 495, 509, 513, 519, 525, 529, 531, 550, 553, 561, 562, 565, 567, 572, 574, 578, 580, 582, 583, 584, 586, 588, 591, 593, 601, 602, 603, 604, 607, 608, 613, 614, 621, 622, 623, 624, 625, 628, 648, 662, 665, 676, 677, 679, 694, 697, 700, 716, 731, 732, 734, 738, 756, 758, 759, 763, 765, 770, 802, 804, 806, 808, 810, 812, 816, 817, 835, 843, 848, 864, 865, 869, 875, 884, 897, 904, 918, 931

Chemokine 696, 760, 841, 9, 935

Chemotherapy 241, 250, 339, 556, 599, 636, 729, 736, 803, 807

Clinical study 174, 241, 296, 334, 339, 342, 350, 359, 367, 369, 375, 390, 396, 397, 402, 416, 421, 423, 435, 440, 441, 447, 453, 456, 458, 467, 473, 477, 488, 489, 509, 510, 513, 524, 531, 538, 543, 546, 549, 582, 628, 636, 676, 694, 731, 804, 860, 861, 866

Clinical trial 226, 331, 332, 333, 334, 335, 336, 346, 347, 349, 350, 351, 352, 359, 367, 369, 370, 375, 381, 382, 383, 396, 397, 398, 400, 402, 416, 420, 421, 422, 423, 425, 435, 440, 441, 443, 445, 447, 450, 453, 456, 458, 462, 473, 474, 476, 477, 480, 483, 484, 485, 488, 489, 500, 502, 505, 506, 509, 513, 519, 521, 524, 525, 526, 529, 531, 538, 542, 543, 544, 546, 549, 582, 861, 868, 887, 94

Coinhibition 185, 480, 617

Costimulation 208, 211, 222, 453, 484, 502, 566, 581, 586, 595, 598, 604, 658, 683, 692, 697, 703, 714, 721, 739, 742, 744, 757, 856, 864, 879, 888

COVID and Immunotherapy 400, 443, 625, 896, 897

Cytokine 104, 106, 128, 165, 173, 208, 209, 211, 212, 218, 222, 281, 29, 292, 303, 319, 342, 383, 4, 402, 435, 473, 484, 489, 502, 509, 526, 556, 563, 567, 571, 578, 584, 596, 599, 605, 606, 683, 689, 692, 703, 708, 710, 713, 715, 716, 717, 718, 719, 720, 721, 723, 724, 729, 738, 742, 744, 752, 764, 765, 770, 776, 793, 816, 841, 848, 853, 861, 871, 876, 879, 898, 9, 908

Dendritic cell 193, 264, 331, 332, 333, 335, 336, 359, 440, 495, 525, 542, 552, 565, 574, 581, 594, 595, 601, 602, 654, 657, 658, 667, 678, 682, 683, 684, 695, 696, 714, 739, 758, 765, 779, 784, 843, 846, 878, 905, 929, 935, 936, 939

Epidemiology 628, 804

Epigenetics 554, 605, 638, 644, 734, 736, 760, 907

Extracellular vesicles/exosomes 572, 654, 761, 842

Gene expression 106, 187, 19, 190, 216, 220, 29, 302, 303, 339, 382, 390, 449, 462, 473, 603, 624, 638, 644, 653, 667, 699, 70, 700, 72, 725, 732, 741, 759, 76, 808, 83, 866, 904, 91, 911, 92, 920, 921, 927, 944, 96

Glycoproteomics 936

Granulocyte 319, 779

Immune adjuvant 157, 218, 222, 223, 367, 396, 476, 495, 500, 578, 581, 596, 599, 600, 620, 703, 710, 721, 725, 726, 738, 739, 743, 760, 763, 765, 767, 768, 770, 853, 860, 897

Immune contexture 285, 29, 3, 303, 38, 390, 41, 50, 54, 583, 602, 641, 733, 739, 828, 833, 887, 905, 911, 917, 921, 929, 930, 935, 936, 937, 96

Immune monitoring 1, 250, 285, 333, 334, 339, 346, 350, 352, 382, 396, 4, 40, 41, 453, 473, 48, 485, 50, 510, 521, 526, 582, 68, 73, 776, 777, 779, 810, 817, 840, 860, 887, 908, 92, 920, 935, 937, 94

Immune suppression 130, 209, 214, 237, 293, 295, 302, 314, 317, 319, 32, 334, 367, 38, 467, 48, 561, 567, 571, 577, 58, 580, 586, 588, 595, 602, 603, 622, 624, 638, 647, 654, 655, 657, 667, 676, 677, 679, 68, 682, 692, 699, 735, 737, 741, 752, 756, 758, 763, 768, 778, 816, 828, 830, 834, 838, 840, 841, 843, 848, 849, 850, 857, 864, 884, 885, 887, 890, 896, 904, 905, 907, 917, 92, 924, 937, 938, 939, 943

Immune tolerance 593, 595, 649, 654, 657, 676, 679, 68, 830, 843, 857, 861, 864, 907, 939

Immune toxicity 116, 212, 236, 237, 238, 239, 293, 336, 350, 381, 68, 721, 731, 802, 803, 804, 806, 807, 808, 810, 812, 816, 817, 867, 898, 908

Immunoscore 818, 927

Inflammation 1, 212, 236, 287, 319, 367, 423, 588, 621, 648, 680, 695, 718, 724, 726, 739, 749, 762, 764, 768, 769, 770, 778, 779, 806, 834, 906, 908, 911, 927, 930, 936, 939

Leukemia/Lymphoma 106, 128, 205, 250, 400, 441, 443, 444, 445, 447, 449, 450, 474, 476, 583, 603, 734, 744, 871, 883

MDSC 319, 369, 375, 580, 586, 593, 600, 607, 622, 649, 678, 682, 758, 763, 768, 769, 849, 870, 875, 887, 931, 939

Metabolism 171, 183, 187, 223, 287, 441, 580, 613, 622, 638, 644, 657, 663, 666, 667, 668, 669, 670, 679, 692, 758, 806, 890, 905, 906

Microbiome 278, 500, 779, 835, 837, 838, 839, 942

Monocyte/Macrophage 104, 208, 209, 214, 220, 261, 287, 301, 302, 317, 335, 352, 38, 48, 515, 570, 571, 580, 593, 603, 614, 617, 641, 649, 653, 667, 676, 677, 678, 680, 681, 682, 695, 696, 699, 726, 733, 758, 763, 769, 778, 779, 784, 822, 828, 834, 842, 845, 853, 865, 866, 875, 878, 880, 881, 885, 890, 906, 908, 917, 919, 920, 924, 935, 939, 940

Myeloid cells 104, 209, 214, 261, 301, 302, 319, 352, 38, 423, 450, 580, 581, 600, 603, 614, 622, 641, 657, 676, 678, 680, 682, 683, 696, 699, 758, 763, 769, 778, 784, 822, 828, 842, 845, 849, 865, 870, 875, 878, 883, 887, 890, 908, 929, 935, 936, 939

Neoantigens 101, 174, 184, 185, 19, 190, 193, 201, 226, 248, 327, 331, 332, 333, 334, 335, 346, 384, 385, 453, 458, 485, 521, 543, 544, 550, 553, 578, 64, 651, 655, 661, 665, 736, 770, 772, 793, 882, 912, 913

NK/NKT cell 113, 116, 128, 129, 130, 159, 162, 164, 169, 171, 181, 191, 197, 205, 208, 210, 215, 216, 222, 305, 314, 400, 402, 435, 444, 477, 48, 510, 582, 584, 606, 621, 638, 646, 662, 688, 689, 703, 704, 710, 727, 742, 744, 747, 789, 834, 839, 850, 864, 865, 878, 940

Pediatric tumors 127, 178, 209, 613, 653, 741, 91, 924, 927

Post-translational modifications 476, 624

Proteomics 187, 333, 582, 83, 90

Radiotherapy 214, 241, 397, 467, 575, 590, 591, 593, 594, 595, 596, 598, 599, 600, 733, 740, 905, 91

Regulatory T cell (Treg cell) 257, 293, 301, 4, 41, 462, 474, 489, 574, 593, 600, 640, 650, 692, 696, 703, 704, 723, 733, 743, 828, 834, 839, 840, 841, 857, 861, 883, 884, 887, 908

RNA 165, 187, 190, 201, 211, 250, 339, 382, 421, 473, 515, 549, 72, 73, 759, 76, 869, 910, 92, 920, 927, 931, 942

Solid tumors 104, 116, 118, 127, 129, 130, 157, 159, 162, 166, 171, 172, 173, 174, 175, 176, 177, 178, 179, 181, 185, 186, 189, 190, 191, 193, 197, 200, 202, 204, 205, 209, 211, 214, 215, 223, 225, 226, 232, 237, 238, 239, 241, 243, 253, 255, 259, 278, 281, 285, 287, 29, 292, 295, 296, 301, 302, 303, 31, 314, 317, 320, 339, 342, 350, 353, 369, 370, 375, 38, 383, 4, 402, 435, 441, 453, 456, 458, 46, 462, 467, 473, 474, 476, 480, 483, 484, 485, 488, 489, 50, 502, 509, 510, 513, 515, 519, 521, 524, 525, 526, 529, 531, 538, 54, 544, 546, 553, 556, 561, 562, 564, 565, 566, 574, 580, 582, 586, 595, 600, 601, 603, 605, 606, 607, 610, 613, 614, 617, 620, 621, 628, 636, 638, 639, 641, 649, 651, 653, 654, 655, 662, 663, 666, 670, 676, 681, 682, 689, 693, 694, 695, 696, 70, 708, 717, 719, 72, 721, 723, 725, 729, 731, 732, 735, 737, 738, 739, 741, 742, 743, 745, 748, 758, 759, 761, 763, 765, 768, 769, 773, 781, 784, 789, 803, 804, 810, 821, 826, 828, 833, 835, 838, 842, 845, 848, 849, 850, 853, 856, 861, 865, 866, 867, 869, 870, 875, 876, 878, 880, 881, 882, 888, 890, 898, 9, 90, 905, 906, 917, 920, 921, 929, 935, 937, 939, 94, 941, 944, 96, 98

Stem cell/cancer-initiating cell 320, 331, 332, 335, 336

Surfaceome 740

Surgery 352, 423, 601, 620

Systems biology 287, 38, 554, 564, 574, 601, 641, 653, 826, 830

T cell 101, 106, 108, 118, 127, 137, 140, 157, 164, 165, 166, 172, 173, 174, 175, 177, 178, 179, 183, 184, 185, 186, 189, 19, 190, 192, 193, 200, 201, 202, 204, 205, 208, 211, 212, 214, 218, 223, 225, 226, 232, 248, 250, 253, 255, 257, 281, 287, 292, 293, 301, 302, 303, 305, 314, 316, 317, 320, 327, 339, 342, 346, 352, 353, 359, 38, 384, 385, 4, 402, 41, 420, 421, 423, 435, 443, 449, 458, 47, 474, 477, 48, 480, 483, 489, 50, 506, 509, 510, 521, 525, 529, 538, 543, 544, 546, 549, 550, 552, 553, 561, 563, 566, 571, 572, 574, 575, 578, 581, 582, 583, 584, 588, 594, 596, 598, 599, 600, 602, 610, 613, 621, 622, 623, 624, 639, 64, 640, 641, 644, 647, 648, 65, 650, 651, 655, 658, 661, 662, 663, 665, 666, 668, 669, 670, 676, 677, 679, 682, 683, 692, 693, 697, 699, 703, 704, 708, 714, 716, 717, 719, 720, 723, 73, 732, 733, 735, 739, 740, 742, 743, 744, 747, 752, 757, 76, 760, 767, 768, 769, 770, 776, 777, 778, 793, 804, 812, 818, 821, 822, 826, 828, 838, 839, 840, 841, 843, 845, 848, 849, 850, 856, 857, 860, 864, 866, 867, 868, 870, 871, 878, 879, 882, 884, 885, 887, 888, 9, 905, 907, 908, 912, 913, 92, 920, 924, 929, 931, 94, 940, 943, 97, 98

T cell lineages 174, 185, 223, 293, 303, 339, 4, 400, 41, 50, 574, 583, 640, 655, 658, 682, 692, 779, 834, 870, 92, 929

Targeted therapy 106, 127, 128, 130, 157, 159, 166, 174, 202, 222, 225, 232, 259, 293, 305, 349, 353, 397, 416, 422, 423, 443, 444, 447, 449, 474, 480, 488, 489, 505, 513, 524, 529, 531, 543, 550, 580, 590, 602, 603, 604, 605, 608, 610, 613, 614, 617, 620, 623, 697, 718, 725, 732, 748, 749, 768, 778, 781, 784, 804, 826, 845, 849, 860, 864, 866, 867, 870, 871, 878, 879, 882, 883, 888, 890, 905, 944

TLR 319, 473, 525, 581, 596, 607, 693, 767, 768, 769, 779, 784

Tumor antigens 101, 108, 116, 174, 177, 185, 189, 190, 192, 202, 211, 218, 225, 226, 334, 350, 367, 382, 421, 453, 458, 480, 485, 543, 544, 549, 553, 578, 581, 582, 623, 64, 65, 651, 654, 655, 661, 665, 714, 720, 725, 740, 743, 760, 772, 776, 777, 781, 784, 793, 826, 840, 860, 871, 882, 883, 912, 913, 97

Tumor evasion 108, 172, 184, 190, 243, 264, 295, 302, 303, 314, 322, 4, 506, 509, 586, 595, 601, 621, 623, 624, 641, 655, 657, 667, 670, 677, 692, 716, 727, 732, 756, 760, 772, 793, 830, 843, 860, 879, 890, 904, 905, 906, 907, 910, 918, 921, 927, 936

Tumor infiltrating lymphocytes (TILs) 101, 165, 166, 171, 172, 174, 175, 176, 177, 179, 181, 183, 184, 185, 186, 187, 190, 193, 204, 208, 212, 214, 215, 222, 223, 253, 255, 256, 257, 281, 287, 293, 301, 302, 303, 305, 309, 314, 320, 326, 327, 334, 342, 353, 38, 382, 384, 385, 4, 41, 420, 423, 458, 462, 48, 50, 506, 509, 54, 543, 544, 550, 553, 566, 570, 575, 594, 595, 596, 600, 602, 603, 608, 621, 622, 623, 638, 639, 64, 640, 641, 644, 646, 647, 650, 651, 655, 661, 662, 665, 666, 669, 670, 677, 679, 683, 692, 695, 696, 703, 708, 715, 716, 718, 72, 723, 732, 735, 737, 739, 740, 743, 745, 747, 752, 756, 757, 758, 76, 760, 762, 763, 768, 769, 776, 793, 818, 822, 826, 828, 829, 830, 834, 839, 841, 845, 846, 850, 853, 856, 860, 868, 879, 884, 9, 905, 906, 908, 912, 917, 918, 92, 921, 929, 930, 935, 939, 94, 96, 98

Tumor microenvironment 113, 130, 171, 172, 174, 175, 183, 200, 209, 212, 214, 215, 250, 259, 264, 281, 287, 29, 292, 293, 295, 301, 302, 303, 305, 309, 314, 317, 319, 32, 320, 322, 326, 334, 339, 342, 352, 369, 375, 38, 382, 383, 390, 4, 40, 41, 420, 423, 46, 47, 473, 48, 50, 506, 509, 519, 550, 553, 554, 556, 561, 564, 566, 567, 570, 571, 574, 575, 577, 58, 580, 581, 583, 586, 593, 594, 600, 602, 603, 605, 607, 608, 614, 621, 622, 623, 624, 638, 639, 641, 644, 646, 647, 648, 650, 653, 654, 655, 657, 662, 663, 668, 669, 670, 677, 679, 680, 681, 682, 683, 689, 692, 693, 696, 699, 710, 713, 715, 72, 721, 723, 725, 727, 73, 731, 732, 733, 737, 739, 740, 741, 743, 747, 756, 757, 758, 759, 76, 760, 762, 763, 765, 768, 769, 776, 778, 821, 822, 828, 83, 830, 833, 834, 838, 839, 841, 842, 845, 848, 849, 850, 853, 856, 861, 866, 869, 870, 876, 879, 884, 885, 890, 904, 906, 908, 91, 917, 918, 919, 92, 920, 921, 924, 927, 929, 930, 931, 935, 936, 937, 938, 940, 941, 942, 943, 944, 96

Tumor stroma 319, 367, 40, 41, 48, 50, 506, 583, 586, 622, 641, 681, 713, 742, 759, 822, 828, 830, 834, 860, 866, 904, 929, 930, 931, 936, 937, 941, 943, 944

Vaccine 157, 211, 214, 218, 332, 333, 334, 335, 336, 350, 381, 382, 420, 421, 422, 453, 483, 485, 505, 521, 542, 549, 575, 578, 581, 582, 594, 598, 599, 625, 65, 696, 767, 770, 772, 773, 776, 777, 778, 779, 793, 860, 913, 936

Late-Breaking Abstract Subject Index

Adoptive immunotherapy 946, 951, 958, 959

Antibody 949, 953

Antigen presenting cells 948, 951

Bioinformatics 946, 962

Biomarkers 945, 946, 955, 961

CAR T cells 946, 958

Checkpoint blockade 947, 949, 950, 955, 956, 960, 962

Chemotherapy 948, 960, 962

Clinical study 948, 950, 951, 953, 954, 957, 959, 960, 961

Clinical trial 948, 949, 951, 952, 954, 955, 956, 957, 958, 959, 960, 961

Costimulation 958

COVID and Immunotherapy 953

Cytokine 957

Dendritic cell 948, 950, 952, 961

Gene expression 946, 953, 955

Granulocyte 953

Immune monitoring 946, 951, 953, 955

Immune toxicity 946

Inflammation 953

Leukemia/Lymphoma 946

Monocyte/Macrophage 951

Myeloid cells 951

NK/NK T cell 957

Radiotherapy 960

Regulatory T cell (Treg cell) 945, 953, 961

RNA 946, 953, 958, 961

Solid tumors 946, 949, 950, 951, 954, 955, 956, 957, 958, 959

Stem cell/cancer-initiating cell 952

Surgery 960

T cell lineages 960

T cell 945, 948, 950, 953, 957, 958, 959, 960, 961

Targeted therapy 951, 954, 955, 959

TLR 950, 961

Tumor antigens 958, 961

Tumor infiltrating lymphocytes (TILs) 945, 947, 955, 960

Tumor microenvironment 945, 947, 950, 951, 957, 960, 961, 962

Vaccine 952, 958