520 Preliminary biomarker and pharmacodynamic (PD) activity of the TGFβ inhibitor SAR439459, alone or in combination with cemiplimab, in a phase 1 clinical study in patients with advanced solid tumors

Debbie Robbrecht; Grob Jean-Jacques; Oliver Bechter; Armando Santoro; Bernard Doger; Ivan Borbath; Butler Marcus; Cheng Tina; Patricia Martin; Bennouna Jaafar; Massimo Di Nicola; Giuseppe Curigliano; Min-Hee Ryu; Alejo Rodriguez -Vida; Dirk Schadendof; Elena Garralda; Giovanni Abbadessa; Brigitte Demers; Amele Amrate; Tun Tun Lin; Manisha Brahmachary; Joon Sange Lee; Joachim Theilhaber; Rob Pomponio; Rui Wang

doi:10.1136/jitc-2021-SITC2021.520

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Regular and Young Investigator Award Abstracts

Clinical Trials In Progress

520 Preliminary biomarker and pharmacodynamic (PD) activity of the TGFβ inhibitor SAR439459, alone or in combination with cemiplimab, in a phase 1 clinical study in patients with advanced solid tumors

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Authors

Debbie Robbrecht Erasmus Medical Centre, Rotterdam, Netherlands PubMed articles Google scholar articles
Grob Jean-Jacques APHM – Hopital de la Timone, Marseille, France PubMed articles Google scholar articles
Oliver Bechter UZ Leuven, NA, Belgium PubMed articles Google scholar articles
Armando Santoro Istituto Clinico Humanitas, NA, Italy PubMed articles Google scholar articles
Bernard Doger Instituto de Investigación Sanitaria Fundación Jiménez Diaz, Madrid, Spain PubMed articles Google scholar articles
Ivan Borbath UCL Saint Luc, NA, Belgium PubMed articles Google scholar articles
Butler Marcus Princess Margaret Hospital, NA, Canada PubMed articles Google scholar articles
Cheng Tina Tom Baker Cancer Centre, NA, Canada PubMed articles Google scholar articles
Patricia Martin Institut Gustave Roussy, NA, France PubMed articles Google scholar articles
Bennouna Jaafar CHU de Nantes – Hotel Dieu, NA, France PubMed articles Google scholar articles
Massimo Di Nicola Istituto Nazionale dei Tumori, NA, Italy PubMed articles Google scholar articles
Giuseppe Curigliano Istituto Europeo Di Oncologia, Milan, Italy PubMed articles Google scholar articles
Min-Hee Ryu Asan Medical Center, NA, Korea, Republic of PubMed articles Google scholar articles
Alejo Rodriguez -Vida Hospital Del Mar, NA, Spain PubMed articles Google scholar articles
Dirk Schadendof Universitatsklinikum Essen, NA, Germany PubMed articles Google scholar articles
Elena Garralda Hospital Universitari dela Vall d’Hebron, Barcelona, Spain PubMed articles Google scholar articles
Giovanni Abbadessa Sanofi, Cambridge, MA, USA PubMed articles Google scholar articles
Brigitte Demers Sanofi, Cambridge, MA, USA PubMed articles Google scholar articles
Amele Amrate Sanofi, Cambridge, MA, USA PubMed articles Google scholar articles
Tun Tun Lin Sanofi, Cambridge, MA, USA PubMed articles Google scholar articles
Manisha Brahmachary Sanofi, Cambridge, MA, USA PubMed articles Google scholar articles
Joon Sange Lee Sanofi, Cambridge, MA, USA PubMed articles Google scholar articles
Joachim Theilhaber Sanofi, Cambridge, MA, USA PubMed articles Google scholar articles
Rob Pomponio Sanofi, Cambridge, MA, USA PubMed articles Google scholar articles
Rui Wang Sanofi, Cambridge, MA, USA PubMed articles Google scholar articles

Citation

Robbrecht D, Jean-Jacques G, Bechter O, et al

Journal for ImmunoTherapy of Cancer 2021;9:doi: 10.1136/jitc-2021-SITC2021.520

Publication history

First published November 10, 2021.

Online issue publication

March 30, 2022

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