PT - JOURNAL ARTICLE AU - Mateus Trinconi Cunha AU - Vinicius Jardim Carvalho AU - Rafael Maffei Loureiro AU - Carlos Eduardo Brantis-de-Carvalho AU - Murilo Bicudo Cintra AU - Gilberto de Castro Junior TI - Letter to the editor: radiomics analysis for predicting pembrolizumab response in patients with advanced rare cancers AID - 10.1136/jitc-2021-003044 DP - 2021 Jul 01 TA - Journal for ImmunoTherapy of Cancer PG - e003044 VI - 9 IP - 7 4099 - http://jitc.bmj.com/content/9/7/e003044.short 4100 - http://jitc.bmj.com/content/9/7/e003044.full SO - J Immunother Cancer2021 Jul 01; 9 AB - A commentary on the original research article: ‘Radiomics analysis for predicting pembrolizumab response in patients with advanced rare cancers’. Of note, the predictor selection process, the cross-validation method, along with the lack of final testing of the developed model with a separated data set may mask overfitting, overestimating performance metrics.