TY - JOUR T1 - Anti-PD-1 Vasculitis of the central nervous system or radionecrosis? JF - Journal for ImmunoTherapy of Cancer JO - J Immunother Cancer DO - 10.1186/s40425-017-0304-8 VL - 5 IS - 1 SP - 96 AU - Roger Sun AU - Francois-Xavier Danlos AU - Samy Ammari AU - Guillaume Louvel AU - Frédéric Dhermain AU - Stéphane Champiat AU - Olivier Lambotte AU - Eric Deutsch Y1 - 2017/12/01 UR - http://jitc.bmj.com/content/5/1/96.abstract N2 - Commentary on « Cerebral vasculitis mimicking intracranial metastatic progression of lung cancer during PD-1 blockade » by Läubli H et al., J Immunother Cancer. 2017;5:46.The authors diagnosed a cerebral tumor-like lymphocytic vasculitis associated with anti-endothelial cell auto-antibodies secondary to anti-PD-1 therapy, treated by surgical resection and corticosteroids. We thought that this diagnosis should be discussed for at least two reasons. First, etiological explorations were not sufficient. Second, the diagnostic of radionecrosis should also be discussed.Abbreviations:ACNSAngiitis of the Central Nervous SystemANCAAnti neutrophil cytoplasmic antibodyMRIMagnetic Resonance ImagingPD-1Programmed cell death 1rCBVRelative cerebral blood volume ER -