PT - JOURNAL ARTICLE AU - James L. Gulley AU - Jay A. Berzofsky AU - Marcus O. Butler AU - Alessandra Cesano AU - Bernard A. Fox AU - Sacha Gnjatic AU - Sylvia Janetzki AU - Shyam Kalavar AU - Vaios Karanikas AU - Samir N. Khleif AU - Ilan Kirsch AU - Peter P. Lee AU - Cristina Maccalli AU - Holden Maecker AU - Jeffrey Schlom AU - Barbara Seliger AU - Janet Siebert AU - David F. Stroncek AU - Magdalena Thurin AU - Jianda Yuan AU - Lisa H. Butterfield TI - Immunotherapy biomarkers 2016: overcoming the barriers AID - 10.1186/s40425-017-0225-6 DP - 2017 Dec 01 TA - Journal for ImmunoTherapy of Cancer PG - 29 VI - 5 IP - 1 4099 - http://jitc.bmj.com/content/5/1/29.short 4100 - http://jitc.bmj.com/content/5/1/29.full SO - J Immunother Cancer2017 Dec 01; 5 AB - This report summarizes the symposium, ‘Immunotherapy Biomarkers 2016: Overcoming the Barriers’, which was held on April 1, 2016 at the National Institutes of Health in Bethesda, Maryland. The symposium, cosponsored by the Society for Immunotherapy of Cancer (SITC) and the National Cancer Institute (NCI), focused on emerging immunotherapy biomarkers, new technologies, current hurdles to further progress, and recommendations for advancing the field of biomarker development.Abbreviations:ALLAcute lymphoblastic leukemiaCRSCytokine release syndromeCyTOFCytometry by time-of-flight, mass cytometryDCDendritic cell(s)EVExtracellular vesicle(s)FDAU.S. Food and Drug AdministrationICSIntracellular cytokine stainingIHCImmunohistochemistryIVDIn vitro diagnosticJITCJournal for immunotherapy of cancerNCINational cancer instituteNKG2DNatural killer group 2DNSCLCNon-small cell lung cancerPBMCPeripheral blood mononuclear cellsPFSProgression-free survivalqPACCQuantitative real-time PCR assisted cell countingSITCSociety for immunotherapy of cancerTCRT cell receptorTDLNTumor-draining lymph nodesTILTumor-infiltrating lymphocyte(s)TLSTertiary lymphoid structuresTMETumor microenvironmentTregRegulatory T cell(s)WGWorking group.