RT Journal Article SR Electronic T1 Immunotherapy biomarkers 2016: overcoming the barriers JF Journal for ImmunoTherapy of Cancer JO J Immunother Cancer FD BMJ Publishing Group Ltd SP 29 DO 10.1186/s40425-017-0225-6 VO 5 IS 1 A1 James L. Gulley A1 Jay A. Berzofsky A1 Marcus O. Butler A1 Alessandra Cesano A1 Bernard A. Fox A1 Sacha Gnjatic A1 Sylvia Janetzki A1 Shyam Kalavar A1 Vaios Karanikas A1 Samir N. Khleif A1 Ilan Kirsch A1 Peter P. Lee A1 Cristina Maccalli A1 Holden Maecker A1 Jeffrey Schlom A1 Barbara Seliger A1 Janet Siebert A1 David F. Stroncek A1 Magdalena Thurin A1 Jianda Yuan A1 Lisa H. Butterfield YR 2017 UL http://jitc.bmj.com/content/5/1/29.abstract AB This report summarizes the symposium, ‘Immunotherapy Biomarkers 2016: Overcoming the Barriers’, which was held on April 1, 2016 at the National Institutes of Health in Bethesda, Maryland. The symposium, cosponsored by the Society for Immunotherapy of Cancer (SITC) and the National Cancer Institute (NCI), focused on emerging immunotherapy biomarkers, new technologies, current hurdles to further progress, and recommendations for advancing the field of biomarker development.Abbreviations:ALLAcute lymphoblastic leukemiaCRSCytokine release syndromeCyTOFCytometry by time-of-flight, mass cytometryDCDendritic cell(s)EVExtracellular vesicle(s)FDAU.S. Food and Drug AdministrationICSIntracellular cytokine stainingIHCImmunohistochemistryIVDIn vitro diagnosticJITCJournal for immunotherapy of cancerNCINational cancer instituteNKG2DNatural killer group 2DNSCLCNon-small cell lung cancerPBMCPeripheral blood mononuclear cellsPFSProgression-free survivalqPACCQuantitative real-time PCR assisted cell countingSITCSociety for immunotherapy of cancerTCRT cell receptorTDLNTumor-draining lymph nodesTILTumor-infiltrating lymphocyte(s)TLSTertiary lymphoid structuresTMETumor microenvironmentTregRegulatory T cell(s)WGWorking group.