Multivariate Cox regression analysis of overall survival in the study population

CharacteristicHR (95% CI)p
ICI type
 Anti-PD-1/PD-L1Reference
 Anti-CTLA-40.85 (0.56–1.28)0.434
 Combination0.78 (0.58–1.05)0.097
Stage IV cancer1.63 (1.03–2.60)0.038
IMDC0.45 (0.34–0.61)< 0.001
Anaerobic antibiotic therapy1.44 (1.11–1.87)0.007

Abbreviations: HR Hazard ratio, CI Confidence interval