Clinical features of the study patients according to use of antibiotic therapy
| Feature | Antibiotic therapy (n = 569) | No antibiotic therapy (n = 257) | p |
|---|---|---|---|
| IMDC, n (%) | 267 (46.9) | 167 (65.0) | < 0.001 |
| Mean duration of IMDC symptoms, days (SD) | 32 (150) | 18 (102) | 0.290 |
| Hospitalization, n (%) | 168 (62.9) | 63 (37.7) | < 0.001 |
| Mean duration of hospitalization, days (SD) | 8 (7) | 7 (5) | 0.143 |
| ICU admission, n (%) | 10 (1.8) | 1 (0.3) | 0.038 |
| Grade of colitis, n (%) | 0.022 | ||
| 1 | 42 (20.7) | 32 (27.6) | |
| 2 | 90 (44.3) | 60 (51.7) | |
| 3 | 65 (32.0) | 19 (16.4) | |
| 4 | 6 (3.0) | 5 (4.3) | |
| Grade of diarrhea, n (%) | 0.098 | ||
| 1 | 77 (28.8) | 52 (31.1) | |
| 2 | 69 (25.8) | 51 (30.5) | |
| 3 | 103 (38.3) | 61 (36.5) | |
| 4 | 18 (6.7) | 3 (1.8) | |
| Mean duration of steroid administration, days (SD) | 52 (44) | 63 (79) | 0.147 |
| Infliximab/vedolizumab administration, n (%) | 52 (19.5) | 31 (18.6) | 0.900 |
| Recurrence of IMDC, n (%) | 42 (15.4) | 41 (24.6) | 0.025 |