Sensitivity and positive predictive value with different tumor size change cut-offs
| Survive Additional t (years) from Week 12 | + 20% | −10% | −30% | |||
|---|---|---|---|---|---|---|
| Sensitivity | PPV | Sensitivitya | PPVb | Sensitivity | PPV | |
| 1 | 92.7% | 82.6% | 65.4% | 87.1% | 48.6% | 91.0% |
| 2 | 93.8% | 66.2% | 71.2% | 75.6% | 55.3% | 82.8% |
| 3 | 94.9% | 57.6% | 76.0% | 69.1% | 60.8% | 77.7% |
aSensitivity: Prob (tumor size change “<= −10%” at Week 12 given surviving additional t years)
bPositive Predictive Value (PPV): Prob(survive additional t years given tumor size change “<= − 10%” at Week 12)