Interaction analyses for individual KIR and KIR ligand genotypes with TTRF
| TTRF | |||||
|---|---|---|---|---|---|
| Line | Treatment | Genotype Group | Number of Events/n | 4 yr Fail Rate (95% CI)a % | Interaction p-value |
| 1 | Maintenance | KIR2DL1+/C2+ | 21/52 | 38 (25–54) | 0.524 |
| 2 | Maintenance | not KIR2DL1+/C2+ | 7/28 | 30 (15–56) | |
| 3 | Non-Maintenance | KIR2DL1+/C2+ | 18/49 | 38 (26–55) | |
| 4 | Non-Maintenance | not KIR2DL1+/C2+ | 6/30 | 21 (9–43) | |
| 5 | Maintenance | KIR2DL2+/C1+ | 11/36 | 32 (18–53) | 0.547 |
| 6 | Maintenance | not KIR2DL2+/C1+ | 17/44 | 38 (25–56) | |
| 7 | Non-Maintenance | KIR2DL2+/C1+ | 6/28 | 24 (10–49) | |
| 8 | Non-Maintenance | not KIR2DL2+/C1+ | 18/51 | 36 (24–52) | |
| 9 | Maintenance | KIR2DL3+/C2+ | 17/56 | 33 (21–50) | 0.982 |
| 10 | Maintenance | not KIR2DL3+/C2+ | 11/24 | 41 (23–64) | |
| 11 | Non-Maintenance | KIR2DL3+/C2+ | 16/60 | 27 (17–43) | |
| 12 | Non-Maintenance | not KIR2DL3+/C2+ | 8/19 | 45 (25–70) | |
| 13 | Maintenance | KIR3DL1+/Bw4+ | 20/54 | 38 (25–55) | 0.055 |
| 14 | Maintenance | notKIR3DL1+/Bw4+ | 8/26 | 29 (15–52) | |
| 15 | Non-Maintenance | KIR3DL1+/Bw4+ | 13/50 | 25 (15–41) | |
| 16 | Non-Maintenance | notKIR3DL1+/Bw4+ | 11/29 | 43 (25–66) | |
a95% Confidence interval; lines 13-14 (bolded text) had a p-value <0.100 and were analyzed further for associations with outcome