Clinical features of responders to nivolumab

n = 72AllResponderNon-responderORRP-value
Age< 6526 (36%)81831%0.07
≥6546 (64%)64013%
GenderMale56 (78%)114520%0.94
Female16 (22%)31319%
ECOG PS043 (60%)133030%< 0.01
≥129 (40%)1283%
HistologyIntestinal31 (43%)52616%0.54
Diffuse41 (57%)93222%
Borrmann classificationType47 (10%)070%0.17
Others65 (90%)145122%
Number of previous chemotherapy229 (40%)82128%0.15
≥343 (60%)63714%
Site of metastasisLymph node59 (82%)144524%0.05
Peritoneum35 (49%)53014%0.28
Liver32 (44%)42813%0.18
Lung10 (14%)1910%0.42
Number of metastatic sites121 (29%)41719%0.96
≥251 (71%)104120%

ECOG PS Eastern Cooperative Oncology Group performance status, ORR objective response rate