Table 1

Patient characteristics

CharacteristicAnti-CTLA4
(n=17)
Anti-PD1
(n=16)
P value
Age (years)
 Median66630.866
 Range38–8037–91
Race
 White15140.998
 Black11
 Asian11
Sex
 Male10120.325
 Female74
Tumor histology
 Adenocarcinoma14120.606
 Squamous cell carcinoma34
Smoking history
 Yes12130.475
 No53
KPS score at diagnosis
 ≥80914
 <80820.057
Prior systemic therapy
 Yes1490.103
 No37
 Number of systemic therapy regimens, mean (range)2.12 (0–8)1.13 (0–4)0.157
Prior radiation therapy
 Yes350.362
 No1411
Prior immunotherapy
 Yes220.9
 No1514
History of autoimmune disease
 Yes110.736
 No1615
 Metastatic sites mean (range)3.1 (2–9)2.4 (2–6)0.207
 ALC change mean (range)−28% (1% to −70%)−19% (−3% to −63%)0.148
  • ALC, absolute lymphocyte counts; KPS, Karnofsky performance status.