Table 2

Best response pre-RECIST V.1.1/post-RECIST V.1.1-defined progression

Best response after RECIST V.1.1 progressionBest response prior to RECIST V.1.1 progression
CRPRSDPDTotal
n=116 patients with response post-RECIST V.1.1 progression and no further PD eventsiCR61305 24 (20.7%)
iPR140610 57 (49.1%)
iSD0 2 122135 (30.2%)
Total7 (6.0%)55 (47.4%)18 (15.5%)36 (31.0%)116
n=116 patients with response post-RECIST V.1.1 progression followed by progression/deathiPR25522 52 (44.8%)
iSD 3 233864 (55.2%)
Total28 (24.1%)28 (24.1%)60 (51.7%)116
  • The bold values identify the 138 responders with iSD or better post-RECIST V.1.1 PD whose duration of response are summarized in online supplementary figure 1.

  • iCR/CR, complete response; iPR/PR, partial response; iSD/SD, stable disease; PD, progression of disease; RECIST, Response Evaluation Criteria in Solid Tumours.