Levels of functioning (EORTC QLQ-C30) by time since last checkpoint inhibitor dose* table 4
| % Responding ‘quite a bit’ or ‘very much’ | ||||||
| Overall (n=90) | Male (n=51) | Female (n=39) | <24 months (n=37) | 24 to <36 months (n=27) | 36+months (n=26) | |
| Physical functioning: Do you… | ||||||
| Have trouble taking a long walk? | 14 | 8 | 23 | 14 | 15 | 15 |
| Have trouble with strenuous activities? | 10 | 8 | 13 | 8 | 7 | 15 |
| Need to stay in bed? | 7 | 4 | 10 | 3 | 4 | 15 |
| Have trouble taking a short walk?† | 3 | 2 | 5 | 0 | 0 | 12 |
| Need help with activities of daily living? | 0 | 0 | 0 | 0 | 0 | 0 |
| Role functioning: Are you limited in… | ||||||
| Work activities? † | 7 | 4 | 10 | 0 | 7 | 15 |
| Leisure activities? | 7 | 6 | 8 | 5 | 7 | 8 |
| Emotional functioning: Do you… | ||||||
| Worry? | 9 | 6 | 13 | 8 | 11 | 8 |
| Feel irritable? | 7 | 4 | 10 | 3 | 11 | 8 |
| Feel depressed? | 6 | 6 | 5 | 5 | 11 | 0 |
| Feel tense? | 7 | 4 | 10 | 5 | 7 | 8 |
| Cognitive functioning: Have you had difficulty… | ||||||
| Concentrating? | 2 | 4 | 0 | 0 | 4 | 4 |
| Remembering? | 7 | 2 | 5 | 5 | 11 | 4 |
| Social functioning: Has your physical condition or treatment… | ||||||
| Interfered with family life? | 4 | 6 | 3 | 3 | 4 | 8 |
| Interfered with social activities? | 8 | 8 | 8 | 3 | 7 | 15 |
| Symptoms/problems | ||||||
| Trouble sleeping | 12 | 10 | 3 | 5 | 15 | 19 |
| Financial problems | 10 | 10 | 10 | 11 | 11 | 8 |
| Constipation | 7 | 2 | 13 | 5 | 7 | 8 |
| Short of breath | 3 | 4 | 3 | 3 | 7 | 0 |
| Diarrhea | 1 | 0 | 3 | 0 | 0 | 4 |
| Poor appetite | 1 | 0 | 3 | 0 | 0 | 4 |
| Nausea and vomiting | 0 | 0 | 0 | 0 | 0 | 0 |
| Global health score (median, range) | 83 (67–100) | 92 (67–100) | 83 (67–100) | 92 (75–100) | 83 (67–100) | 83 (67–100) |
*Differences by sex are not statistically significant. Any significant differences by time since treatment are noted separately.
†Differences by time since treatment are statistically significant.
EORTC QLQ-C30, European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30.