Table 1

Patient characteristics prevaccination and best clinical response during 12-month follow-up after therapeutic human papillomavirus type 16 (HPV16) synthetic long peptide vaccination

Patient study number	Lesion size (cm²)	Histology	HPV16	Best response without additional treatment	Prevaccination biopsy analyzed	3-months postvaccination biopsy analyzed
1	15.5	VIN3	+	PR	+	+
3	3.0	VIN2	+	CR	+	-*
6	8.0	VIN3	+	PR	+	+
9	3.5	VIN3	+	CR	+	+
10	4.0	VIN2	+	PR	+	+
11	25.3	VIN3	+	NR	+	+
14	0.3	VIN3	+	CR	+	+
15	2.0	VIN2	+	NR	+	+
18	2.0	VaIN3	+	NR	+	+
19	4.5	VIN3	+	NR	+	+
20	2.0	VIN2	+	PR	+	+
21	6.5	VIN3	+	NR	+	–
22	2.0	VIN3	+	NR	+	+
24	6.2	VIN3	+	NR	+	+
26	1.0	VIN2	+	NR	+	+
28	9.5	VIN3	+	NR	+	+
29	4.2	VIN2	+	PR	+	+
30	10.3	VIN3	+	PR	+	–
32	1.5	VIN3	+	CR	+	-*
51	19.0	VIN2	+	NR	+	+
52	120.0	VIN3	+	NR	+	+
53	42.0	VIN3	+	PR	+	+
55	104.0	VIN3	+	PR	+	+
57	3.0	VIN3	+	NR	+	+
58	44.0	VIN3	+	CR	+	-*
59	8.0	VIN3	+	NR	+	+
61	12.0	VIN3	+	CR	+	+
62	3.0	VaIN3	+	PR	+	+
63	3.0	VIN3	+	PR	+	+

The data were extracted from our previous report.21
*Vulvar high-grade squamous intraepithelial lesion (vHSIL) already cleared in biopsy.
CR, complete response (100% lesion clearance); NR, no response (<50% lesion size reduction); PR, partial response (≥50% lesion size reduction).