Demographics and first treatment
| Cutaneous (n=283) | Acral (n=22) | Mucosal (n=38) | Uveal (n=30) | |
| Median age (IQR) | 65 (56–75) | 67 (62–73) | 63 (58–71) | 66 (53–72) |
| Gender | 67% male | 59% male | 37% male | 57% male |
| Stage before CPI | ||||
| Stage M1a (%) | 72 (25) | 9 (41) | 6 (16) | 2 (7) |
| Stage M1b (%) | 64 (23) | 6 (27) | 6 (16) | 2 (7) |
| Stage M1c (%) | 87 (31) | 4 (18) | 20 (53) | 25 (83) |
| Stage M1d (%) | 60 (21) | 3 (14) | 6 (16) | 1 (3) |
| First target (%) | ||||
| CTLA-4 | 80 (28) | 6 (27) | 10 (26) | 15 (50) |
| PD-1 or PD-L1 | 95 (34) | 7 (32) | 7 (18) | 4 (13) |
| CTLA-4+PD-1 | 108 (38) | 9 (41) | 21 (55) | 11 (37) |