Table 2

Autoimmune disorders (AD) symptoms and management at baseline

CharacteristicRCC (n=58)
N (%)
UC (n=48)
N (%)
Overall (n=106)
N (%)
AD symptoms
 Asymptomatic41 (71)30 (63)71 (67)
 Symptomatic17 (29)18 (38)35 (33)
Severity of baseline AD symptoms*
 Grade 0 (asymptomatic)41 (71)30 (63)71 (67)
 Grade 113 (22)13 (27)26 (25)
 Grade 23 (5)3 (6)6 (6)
 Grade 3–40 (0)0 (0)0 (0)
 Unknown1 (2)2 (4)3 (3)
Concurrent AD treatment at CPI initiation
 Topical corticosteroids1 (2)2 (4)3 (3)
 Systemic corticosteroids2 (3)3 (6)5 (5)
 Immunomodulatory agents†4 (7)1 (2)5 (5)
  • *Only the worst grade for the same symptom is captured.

  • †Five patients received one of the following treatments: hydroxychloroquine (rheumatoid arthritis), mesalamine (ulcerative colitis), sulfasalazine (ulcerative colitis), teriflunomide (multiple sclerosis) and methotrexate (psoriatic arthritis).

  • CPI, checkpoint inhibitor; RCC, renal cell carcinoma; UC, urothelial carcinoma.