Table 3

Monthly incidence and conditional probability of irAEs

Landmark monthPatients alive on landmark day with no prior irAE, NPatients with irAEs in next 30 days, n (%)Patients with irAEs at any time in the future, n (%)95% CI for future irAE at any time
047047 (10.0)186 (39.6)35.1 to 44.2
141528 (6.8)139 (33.5)29.0 to 38.3
235825 (7.0)111 (31.0)26.3 to 36.1
331213 (4.2)86 (27.6)22.7 to 32.9
427019 (7.0)73 (27.0)21.8 to 32.8
522211 (5.0)54 (24.3)18.8 to 30.5
619311 (5.7)43 (22.3)16.6 to 28.8
71765 (2.8)32 (18.2)12.8 to 24.7
81636 (3.7)27 (16.6)11.2 to 23.2
91462 (1.4)21 (14.4)9.1 to 21.1
101322 (1.5)19 (14.4)8.9 to 21.6
111180 (0.0)17 (14.4)8.6 to 22.1
121093 (2.8)17 (15.6)9.4 to 23.8
  • CI, cumulative incidence; irAEs, immune-related adverse events.