CD38 PBPs, expression levels (MFI) and pattern (CVIF) in T-ALL at diagnosis, MRD and relapse samples
| Samples | Diagnostic | MRD (MRD<5%) | Refractory disease (MRD>5%) | Relapse | ||||
| Number of samples | 188 | 100 | 24 | 35 | ||||
| Median | 95% CI | Median | 95% CI | Median | 95% CI | Median | 95% CI | |
| CD38 PBPs | 85.9 | 82.10 to 89.91 | 74.0 | 58.87 to 83.88 | 79.6 | 65.25 to 96.11 | 85.2 | 74.48 to 93.01 |
| MFI of CD38 in all gated blasts | 4.2 | 3.88 to 4.47 | 4.6 | 3.67 to 6.81 | 4.6 | 3.33 to 8.47 | 5.6 | 4.14 to 8.99 |
| CVIF of CD38 in all gated blasts | 62.8 | 59.32 to 65.55 | 66.4 | 62.28 to 72.38 | 65.0 | 50.22 to 90.73 | 61.8 | 58.43 to 68.02 |
CVIF, coefficient of variation of immunofluorescence; MFI, mean fluorescence intensity; MRD, minimal residual disease; PBPs, positive blasts percentages.