Table 1

Clinicopathological features of 80 high-grade serous ovarian carcinomas

Patient characteristicsAll patients (n).HR-deficient (n). (%)HR-proficient (n). (%)P value
803446
Age≥555217 (50)35 (76) 0.0192
<552817 (50)11 (24)
StageI30 (0)3 (7)0.165
II72 (6)5 (11)
III5020 (59)30 (65)
IV2012 (35)8 (17)
Residual tumorYes6327 (79)36 (78)1
No177 (21)10 (22)
Platinum-sensitivity*Sensitive3019 (60)11 (31) 0.0039
Partial sensitive168 (25)8 (22)
Resistant193 (9)16 (44)
  • *The patients who refused or dropped out of chemotherapy (n=3) and who had no disease progression (n=12) were excluded.

  • †Significant values are underlined.

  • HR, homologous recombination.