Table 2

Treatment-related adverse events in 32 patients

Treatment-related eventsAny gradeGrade 1–2Grade 3Grade 4
Anemia19 (59)18 (56)1 (3)
Neutropenia26 (81)19 (59)6 (19)1 (3)
Thrombocytopenia20 (62)2 (6)7 (22)11 (34)
Nausea29 (91)29 (91)
Vomit4 (13)4 (13)
Constipation7 (22)7 (22)
Fatigue21 (66)21 (66)
Rash1 (3)1 (3)
Fever11 (34)11 (34)
Elevated alanine aminotransferase9 (28)8 (25)1 (3)
Elevated aspartate aminotransferase9 (38)8 (25)1 (3)
Elevated amylase1 (3)1 (3)
Elevated lipase2 (6)1 (3)1 (3)
Hyponatremia1 (3)1 (3)
Peripheral neuropathy2 (6)2 (6)
Hypertension2 (6)2 (6)
  • Data are n (%), unless otherwise specified.

  • No patients had fatal treatment-related adverse events.